Seizures as a manifestation of systemic disease

Although many systemic disorders involve the nervous system and may cause seizures, certain clinical features are unique to some illnesses. This article reviews seizures associated with collagen vascular disorders, vasculitidis, fluid and electrolyte disturbances, endocrine diseases, porphyrias, renal and hepatic disorders, and drugs. Emphasized are features associated with each systemic disorder that may aid in diagnosis and therapy.