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Updated: Jan 27, 2026

Fragmenting Bulk Hydrogels and Processing into Granular Hydrogels for Biomedical Applications
Published on: May 17, 2022
Polyampholyte Hydrogels in Biomedical Applications
Stephanie L Haag1, Matthew T Bernards2
1Department of Chemical & Materials Engineering, University of Idaho, Moscow, ID 83843, USA. haag4885@vandals.uidaho.edu.
Abstract:
Polyampholytes are a class of polymers made up of positively and negatively charged monomer subunits. Polyampholytes offer a unique tunable set of properties driven by the interactions between the charged monomer subunits. Some tunable properties of polyampholytes include mechanical properties, nonfouling characteristics, swelling due to changes in pH or salt concentration, and drug delivery capability. These characteristics lend themselves to multiple biomedical applications, and this review paper will summarize applications of polyampholyte polymers demonstrated over the last five years in tissue engineering, cryopreservation and drug delivery.
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