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Kilogram scale chemical synthesis of 2'-fucosyllactose
Karoly Agoston1, Markus Jondelius Hederos1, Istvan Bajza1
1Glycom A/S, Kogle Alle 4, DK-2970, Hørsholm, Denmark.
Carbohydrate Research
|March 29, 2019
Abstract:
A scalable synthetic procedure to high quality 2'-fucosyllactose, the most abundant oligosaccharide in human breast milk, has been designed and validated in kilogram scale. The synthetic route has been developed to suit industrial environment and contains only a single chromatographic purification step.