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A Strength, Weaknesses, Opportunities and Threats analysis on time lapse
Natalia Basile1, Ibrahim Elkhatib2, Marcos Meseguer3
1IVIRMA Global, Madrid, Spain.
Current Opinion in Obstetrics & Gynecology
|March 30, 2019
Summary
Time-lapse technology offers new ways to evaluate embryo development for improved in vitro fertilization (IVF) success. While promising, its ability to replace conventional methods for embryo selection requires further investigation.
Area of Science:
- Reproductive Medicine
- Embryology
- Assisted Reproductive Technology
Background:
- Conventional microscopy in IVF has limitations, with clinical pregnancy rates per transfer around 30%.
- Improving embryo selection is crucial to reduce multiple pregnancies and enhance implantation potential without compromising success rates.
Purpose of the Study:
- To review time-lapse technology (TLT) in IVF.
- To analyze available TLT models using a SWOT analysis.
- To evaluate TLT's potential to substitute conventional morphology for embryo evaluation.
Main Methods:
- Review of clinical experience and published data on time-lapse systems since 2010.
- Strength, Weaknesses, Opportunities, and Threats (SWOT) analysis of TLT models.
- Correlation of embryo kinetics with blastocyst formation, implantation, and live birth rates.
Main Results:
- Emerging algorithms correlate embryo kinetics with key reproductive outcomes.
- Automation and artificial intelligence are enhancing TLT capabilities.
- Controversies persist regarding TLT's definitive role in replacing conventional morphology assessment.
Conclusions:
- Time-lapse technology presents a significant advancement in monitoring embryonic development.
- Further research is needed to fully establish TLT's superiority over conventional methods for embryo selection.
- The integration of AI and automation holds potential for optimizing TLT's clinical utility.
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