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Updated: Jan 27, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
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Headache and Brain Tumor.

Shahram Hadidchi1, Wesley Surento1, Alexander Lerner1

  • 1Division of Neuroradiology, Department of Radiology, Keck School of Medicine, University of Southern California, 1520 San Pablo Street, Lower Level Imaging L1600, Los Angeles, CA 90033, USA.

Neuroimaging Clinics of North America
|March 31, 2019
PubMed
Summary
This summary is machine-generated.

Most headaches are not caused by serious issues like brain tumors. However, brain tumors can cause headaches, often with other neurological symptoms. Clinical assessment for red flags is crucial before neuroimaging.

Keywords:
Brain tumor treatmentPathophysiology of brain tumor headachePediatric and adult brain tumorPrimary headacheSecondary headache

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Area of Science:

  • Neurology
  • Oncology

Background:

  • Headaches are a common presenting complaint in clinical practice.
  • While most headaches are benign, a subset may indicate serious underlying pathology, such as a brain tumor.

Purpose of the Study:

  • To differentiate common headaches from those potentially indicative of a brain tumor.
  • To highlight the importance of clinical assessment in identifying patients requiring neuroimaging.

Main Methods:

  • Review of clinical presentations of headaches.
  • Analysis of associated neurological signs and symptoms in patients with and without brain tumors.
  • Evaluation of diagnostic criteria for neuroimaging referral.

Main Results:

  • The majority of patients presenting with headaches do not have brain tumors.
  • Headaches associated with brain tumors are frequently accompanied by other neurological deficits.
  • Clinical red flags are essential for guiding the decision for neuroimaging.

Conclusions:

  • A thorough clinical evaluation is paramount in managing patients with headaches.
  • Neuroimaging should be reserved for cases with specific red flags suggestive of serious intracranial pathology.
  • Early identification of potential brain tumor symptoms through careful assessment can guide appropriate diagnostic pathways.