Related Experiment Video
Updated: Jan 27, 2026
08:25
Evaluating the Function of the Foot Core System in the Elderly
Published on: March 11, 2022
3.2K
Anticholinergic Burden in the Elderly Population: An Emerging Concern
Hudson Pierce1, Dominique Thomas1, Tirsit Asfaw1
1Department of Urology, Weill Cornell Medicine, New York, NY, USA.
European Urology
|April 2, 2019
Summary
Antimuscarinic medications for overactive bladder increase anticholinergic burden, posing risks for older adults. Standardizing risk assessment and reevaluating prescribing practices are crucial for elderly patient safety.
Area of Science:
- Geriatric Pharmacology
- Urology
- Clinical Pharmacy
Background:
- Antimuscarinic drugs are a cornerstone therapy for overactive bladder (OAB).
- These medications contribute to the cumulative anticholinergic burden.
- High anticholinergic burden is linked to adverse health outcomes in the elderly population.
Discussion:
- The study highlights the significant risks associated with anticholinergic burden in older patients treated with antimuscarinics for OAB.
- It emphasizes the need for a critical review of current prescribing habits for these medications in geriatric populations.
- The association between anticholinergic burden and adverse events necessitates a proactive approach to patient management.
Key Insights:
- Antimuscarinics, while effective for OAB, elevate anticholinergic burden.
- Adverse outcomes in the elderly are demonstrably linked to this increased burden.
- Current prescribing practices require reevaluation to mitigate risks.
Outlook:
- Standardization of anticholinergic risk assessment tools is recommended.
- Developing evidence-based guidelines for anticholinergic prescribing in the elderly is essential.
- Future research should focus on safer alternatives and optimized management strategies for OAB in older adults.
Related Concept Videos
01:27Emerging Adulthood
656
Jeffrey Arnett's concept of emerging adulthood offers a framework to understand the unique developmental stage between adolescence and full-fledged adulthood, generally from ages 18 to 25. This period is marked by extensive exploration and shifts in identity, relationships, and career choices, a process known in psychology as role experimentation. Emerging adulthood reflects the evolving cultural expectations surrounding adulthood and the dynamic process of personal transformation during...
656
02:04Conservation of Small Populations
16.7K
Small population sizes put a species at extreme risk of extinction due to a lack of variation, and a consequent decrease in adaptability. This weakens the chances of survival under pressures such as climate change, competition from other species, or new diseases. Large populations are more likely to survive pressures such as these, as such populations are more likely to harbor individuals that have genetic variants that are adaptive under new stresses. Small populations are much less...
16.7K
01:25What is Population Genetics?
64.6K
A population is composed of members of the same species that simultaneously live and interact in the same area. When individuals in a population breed, they pass down their genes to their offspring. Many of these genes are polymorphic, meaning that they occur in multiple variants. Such variations of a gene are referred to as alleles. The collective set of all the alleles within a population is known as the gene pool.
64.6K
00:57Population Growth
28.2K
Population size is dynamic, increasing with birth rates and immigration, and decreasing with death rates and emigration. In ideal conditions with unlimited resources, populations can increase exponentially, which plots as a J-shaped growth rate curve of population size against time. This type of curve is characteristic of newly-introduced invasive species, or populations that have suffered catastrophic declines and are rebounding.
28.2K
00:30What are Populations and Communities?
37.5K
Overview
37.5K
01:30Introduction Cardiac Emergencies
325
Cardiac emergencies are critical situations involving the heart that require immediate medical intervention to prevent severe complications or death. These emergencies often arise from underlying heart conditions that impair the heart's ability to function correctly.Types of Cardiac EmergenciesThe most common types of cardiac emergencies include Acute Coronary Syndrome (ACS), myocardial infarction (MI), cardiac arrest, and heart failure.Acute Coronary Syndrome (ACS)Acute Coronary Syndrome (ACS)...
325