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Updated: Jan 27, 2026

Mapping Genome-wide Accessible Chromatin in Primary Human T Lymphocytes by ATAC-Seq
Published on: November 13, 2017
Cell maps on the human genome
Christopher Cherniak1, Raul Rodriguez-Esteban1
1Committee for Philosophy and the Sciences, Department of Philosophy, University of Maryland, College Park, MD 20742 USA.
Background:
We have previously described evidence for a statistically significant, global, supra-chromosomal representation of the human body that appears to stretch over the entire genome.
Results:
Here, we extend the genome mapping model, zooming down to the typical individual animal cell. Its cellular organization appears to be significantly mapped onto the human genome: Evidence is reported for a "cellunculus" - on the model of a homunculus, on the H. sapiens genome.
Conclusions:
Basic cell structure turns out to map similarly onto the total genome, mirrored via genes that express in particular cell organelles (e.g., "nuclear membrane"). Similar cell maps may also appear on individual chromosomes that map topologically on the dorsoventral body axis. This seems to constitute some of the basic structural and functional organization of nucleus and chromosome architecture.
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