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Advances in Corneal Imaging: Current Applications and Beyond.

Kendrick Co Shih1, Ryan Hin-Kai Tse, Yumi Tsz-Ying Lau

  • 1From the Department of Ophthalmology, The University of Hong Kong, Hong Kong; Department of Ophthalmology, Hong Kong Sanatorium and Hospital, Hong Kong; and Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong.

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Recent corneal imaging advances offer objective diagnosis and treatment guidance. This review summarizes key developments in topography, tomography, and optical coherence tomography over five years.

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Area of Science:

  • Ophthalmology
  • Biomedical Engineering
  • Medical Imaging

Background:

  • Corneal imaging is crucial for objective diagnosis and disease monitoring.
  • Limited literature comprehensively reviews recent advances across various corneal imaging modalities.

Purpose of the Study:

  • To provide a concise summary of significant advancements in corneal imaging over the past five years.
  • To review key imaging modalities including topography, tomography, confocal microscopy, densitometry, and angiography.

Main Methods:

  • PubMed literature search conducted on December 11, 2018.
  • Keywords included "cornea", "advances", "topography", "tomography", "optical coherence tomography", and others.
  • Filters applied for human studies, last 5 years, full-text English articles, resulting in 55 selected studies.

Main Results:

  • Reviewed advances in 5 key imaging modalities: topography, tomography, confocal microscopy, densitometry, and angiography.
  • Outlined scientific principles, current applications, limitations, and future potential for each modality.
  • Highlighted recent progress in providing objective, high-resolution visualization of corneal structures and pathologies.

Conclusions:

  • Recent corneal imaging modalities offer immense potential for objective and detailed visualization.
  • Future applications are probable, but technical, economic, and skill-based limitations need addressing.
  • New techniques require robust clinical studies for validation before replacing traditional methods.