[Acute fatty liver in pregnancy]

Area of Science:

• Obstetrics and Gynecology
• Hepatology
• Maternal-Fetal Medicine

Background:

• Acute fatty liver in pregnancy (AFLP) is a rare but life-threatening obstetric complication.
• It is characterized by acute liver dysfunction and/or failure in pregnant women.
• Early recognition is vital to prevent severe maternal and fetal outcomes.

Observation:

• This case report details a 31-year-old primiparous woman with AFLP.
• AFLP presents with symptoms and laboratory findings that can mimic other obstetric emergencies.
• Differential diagnosis includes HELLP syndrome (hemolysis, elevated liver enzymes, low platelets) and severe pre-eclampsia.

Findings:

• The case highlights the critical need for timely diagnosis of AFLP.
• Prompt medical and obstetric intervention can significantly improve outcomes.
• Misdiagnosis can lead to delayed treatment and adverse events.

Implications:

• Emphasizes the importance of considering AFLP in pregnant patients with liver dysfunction.
• Highlights the necessity of accurate differential diagnosis to guide appropriate management.
• Underscores the potential for improved maternal and fetal survival with early detection and intervention.