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Updated: Jan 27, 2026

15N CPMG Relaxation Dispersion for the Investigation of Protein Conformational Dynamics on the µs-ms Timescale
Published on: April 19, 2021
Dynamical Freezing of Relaxation to Equilibrium
Stefano Iubini1,2, Liviu Chirondojan3, Gian-Luca Oppo3
1Department of Physics and Astronomy, University of Padova, Via Marzolo 8, I-35131 Padova, Italy.
Abstract:
We provide evidence of an extremely slow thermalization occurring in the discrete nonlinear Schrödinger model. At variance with many similar processes encountered in statistical mechanics-typically ascribed to the presence of (free) energy barriers-here the slowness has a purely dynamical origin: it is due to the presence of an adiabatic invariant, which freezes the dynamics of a tall breather. Consequently, relaxation proceeds via rare events, where energy is suddenly released towards the background. We conjecture that this exponentially slow relaxation is a key ingredient contributing to the nonergodic behavior recently observed in the negative-temperature region of the discrete nonlinear Schrödinger equation.
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