Related Experiment Video
Updated: Jan 27, 2026

Immunization of Adult Zebrafish for the Preclinical Screening of DNA-based Vaccines
Published on: October 30, 2018
Countering vaccine hesitancy through immunization information systems, a narrative review
Vincenza Gianfredi1, Massimo Moretti2, Pier Luigi Lopalco3
1Post-Graduate School of Hygiene and Preventive Medicine, Department of Experimental Medicine, University of Perugia, Perugia, Italy.
Information technology, specifically immunization information systems (IISs), can combat vaccine hesitancy (VH). These systems offer features like reminders and decision support to boost vaccine confidence and uptake.
Area of Science:
- Public Health
- Infectious Disease Control
- Health Informatics
Background:
- Vaccine hesitancy (VH) poses a significant challenge to public health, impacting infectious disease prevention.
- Multiple factors contribute to the complex decision-making process behind vaccine refusal.
- Information technology presents potential solutions for enhancing vaccination programs.
Purpose of the Study:
- To review the functionalities of Immunization Information Systems (IISs) as a strategy to counter vaccine hesitancy.
- To explore how IIS features can improve vaccination program performance and increase vaccine uptake.
Main Methods:
- Systematic review of IIS functionalities relevant to addressing vaccine hesitancy.
- Analysis of specific IIS features including automatic reminder/recall systems.
- Evaluation of system interoperability, decision support capabilities, web interfaces, and adverse event recording.
Main Results:
- IISs offer features like automatic reminders, interoperability, decision support, and adverse event tracking.
- These systems have the potential to increase vaccine confidence and trust in healthcare providers and policymakers.
- Current research lacks sufficient trials evaluating the efficacy of IIS in countering VH.
Conclusions:
- Immunization Information Systems (IISs) are valuable tools for increasing vaccine confidence and addressing vaccine hesitancy.
- Further research is needed to rigorously evaluate the effectiveness of IIS interventions in combating VH.
More Related Videos
07:32Evaluating the Immune Response of a Nanoemulsion Adjuvant Vaccine Against Methicillin-Resistant Staphylococcus aureus MRSA Infection
Published on: September 1, 2023
10:39Intranasal Administration of Recombinant Influenza Vaccines in Chimeric Mouse Models to Study Mucosal Immunity
Published on: June 25, 2015
Related Concept Videos
Vaccinations
Review and Preview
Percentiles are a type of fractile that partition data into...
Review and Preview
What is the Immune System?
Cancer Vaccines
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Humoral Immune Responses