Related Experiment Video
Updated: Jan 27, 2026
10:28
Reusable Single Cell for Iterative Epigenomic Analyses
Published on: February 11, 2022
1.7K
On the Importance to Acknowledge Transposable Elements in Epigenomic Analyses
Emmanuelle Lerat1, Josep Casacuberta2, Cristian Chaparro3
1CNRS, Laboratoire de Biométrie et Biologie Evolutive, Université de Lyon, Université Lyon 1, UMR 5558, F-69622 Villeurbanne, France. emmanuelle.lerat@univ-lyon1.fr.
Genes
|April 3, 2019
Summary
Transposable elements (TEs) significantly impact genome evolution and gene function. Understanding epigenetic control of TEs is crucial for studying organismal adaptation and genome-wide epigenetic changes.
Area of Science:
- Genomics
- Epigenetics
- Molecular Biology
Background:
- Eukaryotic genomes contain abundant repetitive sequences, including transposable elements (TEs).
- TEs are mobile genetic elements influencing genome evolution and gene function, requiring strict control mechanisms like epigenetic silencing.
- Epigenetic regulation of TEs can indirectly affect nearby genes, potentially driving rapid phenotypic adaptation.
Purpose of the Study:
- To highlight the importance of considering repetitive genomic sequences, particularly TEs, in the context of epigenetic modifications.
- To emphasize the role of TEs in genome evolution and their interplay with epigenetic regulation.
- To discuss the implications of TE-mediated epigenetic changes for organismal adaptation.
Main Methods:
- Review of existing literature on transposable elements and epigenetic regulation.
- Analysis of the impact of TE mobilization on epigenetic landscapes.
- Discussion of bioinformatic tools for studying TEs and their epigenetic effects.
Main Results:
- TEs are a significant component of eukaryotic genomes, impacting genome evolution and gene expression.
- Epigenetic silencing is a primary mechanism for controlling TE activity.
- Epigenetic regulation of TEs can lead to the epigenetic modification of nearby genes, influencing phenotypic adaptation.
Conclusions:
- Repetitive genomic sequences, especially TEs, must be considered when assessing the global impact of epigenetic modifications.
- TEs play a critical role in shaping epigenetic landscapes and facilitating rapid adaptation.
- Bioinformatic tools are essential for investigating the complex interactions between TEs and epigenetic regulation.
Related Concept Videos
01:27Elements and Compounds
103.7K
Pure substances consist of only one type of matter. A pure substance can be an element or a compound. An element consists of only one type of atom, while a compound consists of two or more types of atoms held together by a chemical bond.
Elements
Elements are classified as atomic or molecular based on the nature of their basic units. They are unique forms of matter with specific chemical and physical properties that cannot break down into smaller substances by ordinary chemical reactions. There...
Elements
Elements are classified as atomic or molecular based on the nature of their basic units. They are unique forms of matter with specific chemical and physical properties that cannot break down into smaller substances by ordinary chemical reactions. There...
103.7K
04:00Periodic Classification of the Elements
58.8K
The periodic table arranges atoms based on increasing atomic number so that elements with the same chemical properties recur periodically. When their electron configurations are added to the table, a periodic recurrence of similar electron configurations in the outer shells of these elements is observed. Because they are in the outer shells of an atom, valence electrons play the most important role in chemical reactions. The outer electrons have the highest energy of the electrons in an atom...
58.8K
02:54Classification of Elements and Compounds
73.0K
Pure substances consist of only one type of matter. A pure substance can be an element or a compound. An element consists of only one type of atom, while a compound consists of two or more types of atoms held together by a chemical bond. Elements are classified as atomic or molecular based on the nature of their basic units.
Compounds are pure substances composed of two or more elements in fixed, definite proportions. Compounds are classified as ionic or molecular (covalent) based on the bonds...
Compounds are pure substances composed of two or more elements in fixed, definite proportions. Compounds are classified as ionic or molecular (covalent) based on the bonds...
73.0K
02:35Key Elements for Plant Nutrition
24.1K
Like all living organisms, plants require organic and inorganic nutrients to survive, reproduce, grow and maintain homeostasis. To identify nutrients that are essential for plant functioning, researchers have leveraged a technique called hydroponics. In hydroponic culture systems, plants are grown—without soil—in water-based solutions containing nutrients. At least 17 nutrients have been identified as essential elements required by plants. Plants acquire these elements from the...
24.1K
02:31Elements: Chemical Symbols and Isotopes
125.5K
A chemical symbol is an abbreviation used to indicate an element or an atom of an element. For example, the symbol for mercury is Hg. The same symbol is used to indicate one atom of mercury (microscopic domain) or to label a container of many atoms of the element mercury (macroscopic domain).
Some symbols are derived from the common English name of the element; others are abbreviations of the name in another language — Latin, Greek or German. For example, the symbol for aluminum (common name)...
Some symbols are derived from the common English name of the element; others are abbreviations of the name in another language — Latin, Greek or German. For example, the symbol for aluminum (common name)...
125.5K
00:57The Periodic Table and Organismal Elements
201.2K
Overview
201.2K