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THBS1 as a Key Regulator of Myoblasts: Validation of Its Inhibitory Roles in Skeletal Muscle Development

Ji Qi1, Xinlin Jin1, Jing Wang2

  • 1Shandong Provincial Key Laboratory for Livestock Germplasm Innovation & Utilization, College of Animal Science and Technology, Shandong Agricultural University, Tai'an 271018, China.

Genes
|June 26, 2026
PubMed
Summary

Thrombospondin 1 (THBS1) regulates skeletal muscle growth by activating transforming growth factor-β1 (TGF-β1). Its manipulation impacts myoblast proliferation and differentiation, offering insights into muscle development and disorders.

Keywords:
TGF-β signaling pathwayTHBS1cellular differentiationmyoblastsskeletal muscle

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