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Updated: Aug 9, 2026

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
Published on: June 15, 2011
[The schizophrenic's chilhood]
1Service psychopathologie du développement, hôpital Femme-Mère-Enfant, hospices civils de Lyon, France; Institut des sciences cognitives Marc-Jeannerod, UMR 5304, CNRS et université Claude-Bernard-Lyon-1, France.
Abstract:
Pathology of adolescence and young adult, schizophrenia can begin in very rare cases during childhood. Two early clinical forms of the disorder have been identified by epidemiological studies: one beginning at the age of 15; the other around 9 years old; While many questions remain unsanswered about the neurobiological and environmental factors - common or distinct - of these two clinical phenotype, both are related to a profoun and lasting alteration of the neurocognitive development whose origin would clearly go back to infancy or to the antenal period. Here we will present a possible story back of schizophrenia in the light of the latest neuroscientific studies in imagery and genetics from adolescence to antenal period.
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