Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Factors Influencing Attraction V: Social Skills01:29

Factors Influencing Attraction V: Social Skills

751
Social skills play a crucial role in shaping interpersonal interactions and enhancing individuals' ability to navigate various social environments successfully. These skills contribute to personal and professional success, influencing how others perceive and treat individuals. High social skills provide distinct advantages in numerous settings, including romantic relationships, politics, and legal proceedings. In courtroom settings, for instance, defendants who exhibit strong social skills are...
751
Proteins: From Genes to Degradation02:11

Proteins: From Genes to Degradation

14.3K
Within a biological system, the DNA encodes the RNA, and the nucleotide sequence in the RNA further defines the amino acid sequence in the protein. This is referred to as “The Central Dogma of Molecular Biology” - a term coined by Francis Crick.  Central dogma is a firm principle in biology that defines the flow of genetic information within any life form. The two fundamental steps in central dogma are - transcription and translation.
Transcription is the synthesis of RNA...
14.3K
Multi-input and Multi-variable systems01:22

Multi-input and Multi-variable systems

404
Cruise control systems in cars are designed as multi-input systems to maintain a driver's desired speed while compensating for external disturbances such as changes in terrain. The block diagram for a cruise control system typically includes two main inputs: the desired speed set by the driver and any external disturbances, such as the incline of the road. By adjusting the engine throttle, the system maintains the vehicle's speed as close to the desired value as possible.
In the absence of...
404
Gene Flow02:39

Gene Flow

37.6K
Gene flow is the transfer of genes among populations, resulting from either the dispersal of gametes or from the migration of individuals.
37.6K
Gene Families01:57

Gene Families

9.9K
Gene families consist of groups of genes proposed to have originated from a common ancestor. Typically these arise through events in which a gene or genes are mistakenly duplicated during cell division. Unlike their parent genes (which are subject to selection pressure to maintain function), these gene copies do not need to preserve their sequences and may evolve at a relatively faster rate.
Occasionally these regions can be adapted to take on new roles within the organism, becoming novel genes...
9.9K
Gene Therapy00:59

Gene Therapy

27.4K
Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be...
27.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Rapid adaptation and extinction in synchronized outdoor evolution experiments of <i>Arabidopsis</i>.

Science (New York, N.Y.)·2026
Same author

Changes in phenology can alter patterns of natural selection: the joint evolution of germination time and postgermination traits.

The New phytologist·2023
See all related articles

Related Experiment Video

Updated: Jan 26, 2026

Acquisition of a High-precision Skilled Forelimb Reaching Task in Rats
08:59

Acquisition of a High-precision Skilled Forelimb Reaching Task in Rats

Published on: June 22, 2015

10.9K

Multi-tasking as an ancient skill: When one gene does many things well.

Kathleen Donohue1

  • 1Department of Biology, Duke University, Durham, North Carolina.

Molecular Ecology
|April 3, 2019
PubMed
Summary

Genes often have multiple functions, a concept known as pleiotropy. Research shows pleiotropic genes can still adapt, challenging the idea that they limit evolution.

Area of Science:

  • Evolutionary genetics
  • Molecular biology
  • Plant science

Background:

  • Pleiotropy, where a single gene influences multiple traits, is common in many organisms.
  • It's often viewed as an evolutionary constraint due to conflicting selection pressures on different traits.
  • Genes regulating flowering time, like FLOWERING LOCUS C (FLC) in Arabidopsis thaliana, exemplify pleiotropy.

Discussion:

  • A study on PERPETUAL FLOWERING 1 (PEP1), an FLC ortholog in Arabis alpina, investigated its pleiotropic effects.
  • The research explored how pleiotropy persists across species, even as gene functions evolve under natural selection.
  • Findings suggest that taxon-specific natural selection can drive the evolution of gene function despite pleiotropy.

Key Insights:

  • Pleiotropy is prevalent and persists through taxonomic diversification in flowering-time genes.

More Related Videos

Study Motor Skill Learning by Single-pellet Reaching Tasks in Mice
06:04

Study Motor Skill Learning by Single-pellet Reaching Tasks in Mice

Published on: March 4, 2014

22.2K
A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills
07:31

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills

Published on: February 13, 2020

7.4K

Related Experiment Videos

Last Updated: Jan 26, 2026

Acquisition of a High-precision Skilled Forelimb Reaching Task in Rats
08:59

Acquisition of a High-precision Skilled Forelimb Reaching Task in Rats

Published on: June 22, 2015

10.9K
Study Motor Skill Learning by Single-pellet Reaching Tasks in Mice
06:04

Study Motor Skill Learning by Single-pellet Reaching Tasks in Mice

Published on: March 4, 2014

22.2K
A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills
07:31

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills

Published on: February 13, 2020

7.4K
  • Despite pleiotropy, the specific functions of genes can evolve in response to environmental pressures.
  • This challenges the traditional view of pleiotropy as a significant constraint on adaptation.

    • Outlook:

    • Further research into pleiotropic gene evolution in natural settings is warranted.
    • Understanding how pleiotropy interacts with adaptation can refine evolutionary models.
    • This work opens new avenues for studying gene function and evolutionary potential.