Related Experiment Video
Updated: Jan 26, 2026
10:33
Generation of Alginate Microspheres for Biomedical Applications
Published on: August 12, 2012
21.8K
Biomedical Applications of DNA-Based Molecular Devices
Shaoli Liu1,2, Qiao Jiang1, Yuanning Wang1,3
1CAS Key Laboratory of Nanosystem and Hierarchical Fabrication, CAS Center for Excellence in Nanoscience, National Center for NanoScience and Technology, Beijing, 100190, China.
Advanced Healthcare Materials
|April 3, 2019
Summary
DNA nanotechnology enables programmable nanodevices for biomedical uses. This review highlights DNA nanodevices for cellular imaging and drug delivery, discussing future opportunities.
Area of Science:
- Biotechnology
- Nanotechnology
- Molecular Biology
Background:
- Deoxyribonucleic acid (DNA) serves as a programmable building block for nanostructure construction.
- DNA nanotechnology has advanced, yielding dynamic molecular devices with complex nanostructures.
- DNA nanodevices offer programmability and biocompatibility, driving applications in biological systems.
Purpose of the Study:
- To review recent advancements in designing DNA nanodevices with programmable functions for biomedical applications.
- To highlight the in vitro and in vivo applications of DNA nanodevices in cellular imaging and systemic drug delivery.
- To discuss current challenges and future opportunities in the field of DNA-based nanodevices.
Main Methods:
- Literature review of recent research in DNA nanotechnology and its biomedical applications.
- Analysis of studies focusing on the design and construction of DNA-based nanodevices.
- Synthesis of information regarding the functional applications of DNA nanodevices in cellular imaging and drug delivery.
Main Results:
- DNA nanodevices have demonstrated sophisticated programmable functions for biomedical applications.
- Successful in vitro and in vivo applications include enhanced cellular imaging and targeted systemic drug delivery.
- The field shows significant progress in developing versatile and biocompatible DNA-based nanomachines.
Conclusions:
- DNA nanotechnology provides a powerful platform for developing advanced biomedical tools.
- Programmable DNA nanodevices hold great promise for revolutionizing diagnostics and therapeutics.
- Further research is needed to overcome challenges and fully realize the potential of DNA nanodevices in medicine.
Related Concept Videos
01:20Applications of Molecular Taxonomy
541
Molecular taxonomy has revolutionized the understanding and classification of bacteria, providing precise insights into their diversity, evolutionary relationships, and ecological roles. By utilizing molecular techniques such as DNA sequencing and fingerprinting, researchers have made significant strides in various fields related to bacterial studies.Resolving Taxonomic AmbiguitiesMolecular taxonomy has been instrumental in distinguishing closely related bacterial species initially thought to...
541
02:27DNA Base Pairing
33.1K
Erwin Chargaff’s rules on DNA equivalence paved the way for the discovery of base pairing in DNA. Chargaff’s rules state that in a double-stranded DNA molecule,
33.1K
02:27DNA Base Pairing
32.1K
32.1K
02:27Base-pairing and DNA Repair
91.0K
91.0K
01:34DNA Isolation
199.2K
DNA from cells is required for many biotechnology and research applications, such as molecular cloning. To remove and purify DNA from cells, researchers use various methods of DNA extraction. While the specifics of different protocols may vary, some general concepts underlie the process of DNA extraction.
199.2K
02:00Molecular Models
43.6K
Physical models representing molecular architectures of chemical compounds play essential roles in understanding chemistry. The use of molecular models makes it easier to visualize the structures and shapes of atoms and molecules.
43.6K