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Related Concept Videos

Adhesion01:14

Adhesion

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Adhesion occurs when one type of molecule is attracted to a different molecule. Water exhibits adhesive properties in the presence of polar surfaces, such as glass or cellulose in plants. For instance, when water is poured into a glass, the positively charged hydrogen molecules of water are more attracted to the negatively charged oxygen molecules in the silica than to the oxygen in neighboring water molecules.
Capillary action is a result of water’s adhesive tendencies. When a narrow...
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Cell Adhesion in Plants01:14

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Plants have rigid cell walls that are made up of cell wall polysaccharides that mediate cell-cell adhesion. The primary cell walls of plants consist of two independent and interacting polysaccharide networks: a pectin matrix that embeds the second network comprising cellulose and hemicelluloses.
Pectins are complex heteropolymers mainly composed of negatively-charged α-D-glucopyranosyl uronic acid and some neutral glycosyl residues such as α-L-rhamnopyranose, α-L-arabinofuranose,...
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Vibrating Concrete01:19

Vibrating Concrete

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Mechanical vibrators are instrumental in compacting newly poured concrete within formwork and around reinforcements. This process is essential to eliminate trapped air pockets and establish a dense concrete mass. One widely used method is vibrating by internal vibrators, often referred to as a poker vibrator or immersion vibrator. It is rapidly inserted through the full depth of the freshly laid concrete and slightly extends into the layer below it (which remains in a plastic state). Consistent...
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Immunoglobulin-like Cell Adhesion Molecules01:31

Immunoglobulin-like Cell Adhesion Molecules

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Immunoglobulin-like cell adhesion molecules or Ig-CAMs are a versatile group of cell surface glycoproteins belonging to the immunoglobulin protein superfamily. Ig-CAMs possess the characteristic immunoglobulin protein domains and other domains such as the fibronectin type III domain. The Ig domains are glycosylated to varying degrees in different Ig-CAMs.
Ig-CAMs exhibit either homophilic binding (to other Ig-CAMs) or heterophilic binding (to other ligands such as integrins). While most Ig-CAMs...
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Cell Adhesion Molecules - Types and Functions01:20

Cell Adhesion Molecules - Types and Functions

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Cell adhesion molecules (CAMs) are pivotal to multicellularity and the coordinated functioning of tissues and organ systems. They enable physical interactions between cells and provide mechanical strength to tissues. They also function as receptors for signal transmission across the plasma membrane. The CAMs are broadly classified into four families - integrins, cadherins, selectins, and immunoglobulin-like CAMs (IgCAMs).
CAM Families
The Integrin family of proteins is primarily  involved...
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IR Spectroscopy: Molecular Vibration Overview01:24

IR Spectroscopy: Molecular Vibration Overview

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When Infrared (IR) radiation passes through a covalently bonded molecule, the bonds transition from lower to higher vibrational levels. The fundamental vibrational motions that result in infrared absorption can be classified as stretching or bending vibrations.
Stretching vibrations are vibrational motions that occur along the bond line, changing the bond length or distance between two bonded atoms. They are further distinguished as symmetric or asymmetric. In symmetric stretching, the...
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Related Experiment Video

Updated: Jan 26, 2026

Control of Cell Adhesion using Hydrogel Patterning Techniques for Applications in Traction Force Microscopy
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Adhesive cell patterning technique using ultrasound vibrations.

Kentaro Tani1, Koji Fujiwara1, Daisuke Koyama1

  • 1Faculty of Science and Engineering, Doshisha University, 1-3 Tataramiyakodani, Kyotanabe, Kyoto 610-0321, Japan.

Ultrasonics
|April 3, 2019
PubMed
Summary
This summary is machine-generated.

Ultrasound vibration patterning in cell culture dishes can control cell growth. While strong vibrations inhibit HeLa cell proliferation, they do not impact cell viability, offering a method for cell growth regulation.

Keywords:
Acoustic radiation forceCell cultureCell manipulationCell patterningFlexural vibrationHeLa cell

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Area of Science:

  • Biotechnology
  • Cell Biology
  • Acoustics

Background:

  • Cell patterning is crucial for understanding cell behavior and tissue development.
  • Ultrasound technology offers potential for non-invasive manipulation in biological systems.

Purpose of the Study:

  • To investigate the effects of ultrasound vibration on cell patterning and growth.
  • To explore the potential of ultrasound-induced flexural vibrations for controlling cell culture.

Main Methods:

  • Development of an ultrasound cell culture dish with piezoelectric-induced resonance flexural vibrations.
  • Observation of HeLa cell growth under ultrasound excitation for 24 hours.
  • Finite element analysis to predict the acoustic field and vibration distribution.

Main Results:

  • High-intensity ultrasound vibrations significantly inhibited HeLa cell growth.
  • Cell viability remained unaffected by the ultrasound treatment.
  • Cell growth patterns were strongly correlated with the acoustic field and dish vibration distribution.

Conclusions:

  • Ultrasound vibration patterning is a viable technique for controlling cell growth in culture.
  • The flexural vibration of the culture dish can be used to regulate cell proliferation without compromising viability.