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Published on: April 17, 2021
Microcatheter collateral channel tracking failure in retrograde percutaneous coronary intervention for chronic total
Xin Zhong1, Lei Ge, Jianying Ma
1Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.
Insights
Microcatheter collateral channel tracking failure occurred in 22.5% of retrograde percutaneous coronary intervention (PCI) procedures. Angiographic factors like collateral channel grade and entry/exit angles predicted failure, guiding management strategies.
Area of Science:
- Cardiology
- Interventional Cardiology
- Vascular Biology
Background:
- Retrograde percutaneous coronary intervention (PCI) is crucial for treating chronic total occlusions (CTOs).
- Microcatheter manipulation within collateral channels (CCs) is a key step in retrograde PCI.
- Failure to track CCs with a microcatheter can impede successful CTO revascularization.
Purpose of the Study:
- To determine the incidence of microcatheter collateral channel (CC) tracking failure during retrograde PCI for CTOs.
- To identify predictors of microcatheter CC tracking failure.
- To describe management strategies employed after initial tracking failure.
Main Methods:
- Retrospective analysis of prospectively collected data from 371 retrograde CTO-PCI procedures.
- Focus on 280 procedures with initial wire CC tracking success.
- Statistical analysis to identify independent predictors of microcatheter CC tracking failure.
Main Results:
- Initial microcatheter CC tracking failure occurred in 22.5% of procedures.
- For septal collaterals, predictors included CC grade 0-1, entry angle <90°, exit angle <90°, and specific microcatheter use.
- For epicardial collaterals, CC 1 was the sole predictor.
- Management involved microcatheter switching (61.9%) and adjunct techniques.
Conclusions:
- Microcatheter CC tracking failure is a significant challenge in retrograde CTO-PCI, occurring in nearly a quarter of cases post-wire success.
- Angiographic features like collateral quality and channel angles are key predictors.
- Understanding these predictors aids in optimizing procedural strategy and success rates.
Aims:
This study sought to demonstrate the incidence, predictors, and management of microcatheter collateral channel (CC) tracking failure in retrograde percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) lesions.
Methods And Results:
Prospectively collected data from 371 consecutive retrograde CTO-PCI procedures between March 2015 and January 2018 were retrospectively analysed. The incidence of initial microcatheter CC tracking failure was 22.5% in 280 procedures with wire CC tracking success. For septal collaterals, CC grade 0-1 collaterals (odds ratio [OR]: 8.3; p<0.001), channel entry angle <90° (OR: 13.0; p=0.001), channel exit angle <90° (OR: 44.3; p=0.004), and Finecross MG as initial microcatheter (OR: 2.7; p=0.032) were independently related to initial microcatheter CC tracking failure. Meanwhile, the only predictor for epicardial collaterals was CC 1 collaterals (OR: 26.9; p<0.001). Frequently applied solutions included microcatheter switching (61.9%), and microcatheter switching combined with GUIDEZILLA (14.3%) or anchoring balloon technique (6.3%).
Conclusions:
Initial microcatheter CC tracking failure was found in nearly one quarter of procedures after wire CC tracking success. Independent angiographic predictors of initial microcatheter CC tracking failure included CC 0-1 collaterals, channel entry angle <90°, and channel exit angle <90° for septal collaterals, and CC 1 collaterals for epicardial collaterals.
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