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Updated: Jan 26, 2026

Functional Characterization of Regulatory Macrophages That Inhibit Graft-reactive Immunity
Published on: June 7, 2017
TREMendous Macrophages Inhibit Hair Growth
Tim Dalessandri1, Maria Kasper1
1Karolinska Institutet, Department of Biosciences and Nutrition & Center for Innovative Medicine, NEO, 141 83 Huddinge, Sweden.
Abstract:
Tissue-resident immune cells with potent sensing and effector functions are well-placed to fundamentally aid tissue homeostasis via crosstalk with stem cells. In this issue of Cell Stem Cell, Wang et al. (2019) identify a dermis-resident TREM2+ macrophage subpopulation that promotes hair follicle stem cell quiescence via cytokine-mediated JAK-STAT signaling.
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