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Updated: Jan 26, 2026

Technical Aspects of the Mouse Aortocaval Fistula

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Published on: July 11, 2013

Dermatologic Aspects of Systemic Vasculitis.

David S Younger¹, Andrew Carlson²

¹Department of Neurology, Division of Neuro-Epidemiology, New York University School of Medicine, New York, NY 10016, USA; School of Public Health, City University of New York, New York, NY, USA.

Neurologic Clinics

|April 7, 2019

Summary

Vasculitis, inflammation of blood vessels, can manifest on the skin with various symptoms. Idiopathic cutaneous leukocytoclastic vasculitis is a common form, often diagnosed with skin biopsy and clinical correlation.

Keywords:

Dermatology Infection Vasculitis

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Area of Science:

Dermatology
Pathology
Immunology

Background:

Systemic and localized vasculitis commonly affects the skin and subcutaneous tissue.
Factors like lower extremity stasis and cold exposure can influence vasculitis presentation.
Initial skin signs include discoloration, swelling, hemorrhage, and necrosis.

Purpose of the Study:

To summarize the clinical presentation and diagnostic considerations for cutaneous vasculitis.
To highlight the characteristics of idiopathic cutaneous leukocytoclastic vasculitis.

Main Methods:

Review of clinical and pathological features of vasculitis affecting the skin.
Emphasis on the diagnostic process involving clinical history, physical examination, and laboratory findings.

Main Results:

Cutaneous vasculitis presents with diverse and dynamic patterns.
Idiopathic cutaneous leukocytoclastic vasculitis accounts for half of cases, often without a clear trigger or systemic involvement.
Skin biopsy and dermatopathology are crucial but require integration with clinical data.

Conclusions:

Accurate diagnosis of cutaneous vasculitis necessitates a comprehensive approach.
Correlation of dermatopathology with clinical findings is essential for diagnosis.