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Updated: Jan 26, 2026

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy
Published on: May 8, 2018
Hepatobiliary Imaging in Liver-directed Treatments
Caren van Roekel1, Margot T M Reinders1, Sandra van der Velden1
1Department of Radiology and Nuclear Medicine, University Medical Center Utrecht (UMCU), Utrecht, the Netherlands.
Hepatobiliary scintigraphy (HBS) is a nuclear imaging technique that reliably assesses liver function, especially in patients with impaired liver function. It helps predict post-surgery liver failure risk and is useful in radioembolization treatments.
Area of Science:
- Nuclear medicine
- Medical imaging
- Hepatology
Background:
- Hepatobiliary scintigraphy (HBS) is an emerging nuclear imaging technique.
- It assesses global and regional liver function, proving reliable for impaired liver function (e.g., cirrhosis, post-chemotherapy).
Purpose of the Study:
- To highlight the utility of HBS in assessing liver function.
- To discuss its role in predicting posthepatectomy liver failure and its use in radioembolization.
Main Methods:
- Utilizes Technetium-99m tracers (iminodiacetic acid or galactosyl human serum albumin).
- Calculates global and regional liver function distribution.
Main Results:
- HBS is the most reliable method for assessing liver function distribution.
- It accurately predicts future liver remnant function in hemihepatectomy candidates.
Conclusions:
- HBS is crucial for assessing liver function, particularly in complex cases.
- Its applications are expanding, including pre-surgical planning and radioembolization treatments.
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