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Author Spotlight: Exploring the Antibacterial Effects of Zinc Oxide Nanoparticles in Overcoming Antibiotic Resistance
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Proline-based hydroxamates targeting the zinc-dependent deacetylase LpxC: Synthesis, antibacterial properties, and

Dmitrii V Kalinin1, Oriana Agoglitta2, Hélène Van de Vyver3

  • 1Institute of Organic Chemistry, University of Hamburg, Martin-Luther-King-Platz 6, 20146 Hamburg, Germany; German Center for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems, Germany; Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Corrensstr. 48, 48149 Münster, Germany; Cells-in-Motion Cluster of Excellence (EXC 1003 - CiM), University of Münster, Germany.

Bioorganic & Medicinal Chemistry
|April 8, 2019
PubMed

Keywords:
AntibacterialsChiral pool synthesisLpxC inhibitorsMMP inhibitorsMolecular docking studiesProline derivativesStructure-activity relationships

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