Related Experiment Video
Updated: Jan 26, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 4, 2010
Severe Asthma Global Evaluation (SAGE): An Electronic Platform for Severe Asthma
Eve Denton1, Fiona Hore-Lacy2, Naghmeh Radhakrishna2
1Allergy, Asthma & Clinical Immunology, The Alfred Hospital, Melbourne, Australia; Public Health & Preventive Medicine, Monash University, Melbourne, Australia.
A new electronic platform, Severe Asthma Global Evaluation (SAGE), streamlines severe asthma assessment. This tool improves symptom control and reduces exacerbations in patients with difficult-to-manage asthma.
Area of Science:
- Pulmonary Medicine
- Digital Health
- Clinical Informatics
Background:
- Severe asthma management is complex and heterogeneous, with suboptimal outcomes from ad hoc outpatient assessments.
- Systematic evaluation is recommended by international guidelines for improving severe asthma care.
- Electronic templates can enhance physician performance and clinical processes in specialized evaluations.
Purpose of the Study:
- To develop and validate the Severe Asthma Global Evaluation (SAGE) electronic platform for streamlining severe asthma systematic evaluation.
- To integrate patient questionnaires, clinical modules, and data reporting into a single, efficient system.
- To ensure compatibility with international severe asthma registries for research collaboration.
Main Methods:
- Development of the SAGE electronic platform using Research Electronic Data Capture (REDCap).
- Incorporation of pre-consultation patient questionnaires, asthma/comorbidity modules, and a clinical summary.
- Inclusion of nurse educator and panel discussion modules, with automated report generation.
Main Results:
- SAGE streamlines severe asthma evaluation, incorporating 282 clinician fields with an average completion of 169 fields per consultation.
- The platform features 34 autocalculations and 20 decision support tools to enhance efficiency.
- SAGE is compatible with the International Severe Asthma Registry, including all 95 core variables.
Conclusions:
- The developed SAGE electronic platform facilitates comprehensive yet streamlined systematic evaluation of severe asthma.
- SAGE use improves symptom control and reduces exacerbations in patients with difficult asthma.
- The platform is freely available, enhancing severe asthma management, audit, and international research collaboration.
Related Concept Videos
Asthma-I: Introduction
Asthma-II: Pathophysiology and Classification
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Asthma: Pathogenesis and Management
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma-III: Symptoms and Complications
Classification of Asthma
Asthma-IV: Diagnostic and Management
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Asthma-IV: Nursing Management
First, in...

