Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Function Tests01:25

Pulmonary Function Tests

779
Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
779
Significance Testing: Overview01:04

Significance Testing: Overview

11.6K
Significance testing is a set of statistical methods used to test whether a claim about a parameter is valid. In analytical chemistry, significance testing is used primarily to determine whether the difference between two values comes from determinate or random errors. The effect of a particular change in the measurement protocol, analyst, or sample itself can cause a deviation from the expected result. In the case of a suspected deviation/outlier, we need to be able to confirm mathematically...
11.6K
Serum Studies: Renal Function Tests01:24

Serum Studies: Renal Function Tests

403
Renal function tests are crucial for assessing kidney health, monitoring disease progression, and evaluating the kidneys' efficiency in waste elimination, fluid balance, and electrolyte regulation. These tests offer critical insights into kidney function, even though routine measurements may appear normal until there is a significant decline in the glomerular filtration rate or GFR. Typically, signs of kidney impairment only become evident when the GFR falls to about 50% of its normal level.
403
In Vitro Drug Release Testing: Overview, Development and Validation01:10

In Vitro Drug Release Testing: Overview, Development and Validation

324
In vitro dissolution and drug release tests assess how quickly and how much of a drug is released from its dosage form into an aqueous medium under standardized laboratory conditions. These tests are essential tools in pharmaceutical development and quality assurance, offering insight into the drug's performance before clinical use.During formulation development, dissolution testing identifies incomplete or inconsistent drug release issues. It also supports decisions on selecting the optimal...
324
Overview of Pulmonary Circulation01:19

Overview of Pulmonary Circulation

2.9K
The pulmonary circulation is a vital system in our body that acts as a bridge between the respiratory and cardiovascular systems. It serves as a transport network for deoxygenated blood from the heart to the lungs and then returns oxygen-rich blood back to the heart.
The process begins with the right ventricle of the heart pumping deoxygenated blood into the pulmonary trunk. This large vessel extends about 5 centimeters before splitting into the left and right pulmonary arteries. These arteries...
2.9K
Testes: Histology01:27

Testes: Histology

2.9K
A tough, fibrous membrane, the tunica albuginea, covers the testes, extending inward to form fibrous partitions or septa, dividing them into internal compartments called lobules. Each lobule has 1 to 3 tightly coiled seminiferous tubules where sperm production occurs. These tubules merge into a tubular network at the back of the testis, known as the rete testis. It connects to 15 to 20 efferent ductules, leading to the epididymis.
The spermatogenic cells, responsible for producing sperm, are...
2.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

As-needed inhaled corticosteroids in asthma: from evidence to implementation.

Current opinion in pulmonary medicine·2026
Same author

ACR Appropriateness Criteria® Acute Respiratory Illness in Immunocompetent Patients: 2024 Update.

Journal of the American College of Radiology : JACR·2025
Same author

Recent evidence for stepping down severe asthma therapies.

Current opinion in pulmonary medicine·2025
Same author

Biologics in severe asthma: a state-of-the-art review.

European respiratory review : an official journal of the European Respiratory Society·2025
Same author

Peripheral airways dysfunction measured by oscillometry differentiates asthma from inducible laryngeal obstruction.

Respiratory medicine·2024
Same author

Asthma and Hyperglycemia: Exploring the Interconnected Pathways.

Diagnostics (Basel, Switzerland)·2024

Related Experiment Video

Updated: Jan 26, 2026

Integration of Brain Tissue Saturation Monitoring in Cardiopulmonary Exercise Testing in Patients with Heart Failure
04:20

Integration of Brain Tissue Saturation Monitoring in Cardiopulmonary Exercise Testing in Patients with Heart Failure

Published on: October 1, 2019

6.2K

Pulmonary Function Testing and Cardiopulmonary Exercise Testing: An Overview.

Katherine Krol1, Mary Anne Morgan1, Sandhya Khurana2

  • 1Pulmonary and Critical Care Medicine, University of Rochester School of Medicine, University of Rochester Medical Center, 601 Elmwood Avenue, Box 692, Rochester, NY 14642, USA.

The Medical Clinics of North America
|April 9, 2019
PubMed
Summary
This summary is machine-generated.

Diagnosing respiratory symptoms can be challenging. Pulmonary function testing offers objective measures to aid in diagnosis and treatment planning for respiratory conditions.

Keywords:
Cardiopulmonary exercise testDiffusing capacityPulmonary function testSpirometry

More Related Videos

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans
07:26

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans

Published on: October 17, 2018

21.3K
Surgical Placement of Catheters for Long-term Cardiovascular Exercise Testing in Swine
12:37

Surgical Placement of Catheters for Long-term Cardiovascular Exercise Testing in Swine

Published on: February 9, 2016

13.9K

Related Experiment Videos

Last Updated: Jan 26, 2026

Integration of Brain Tissue Saturation Monitoring in Cardiopulmonary Exercise Testing in Patients with Heart Failure
04:20

Integration of Brain Tissue Saturation Monitoring in Cardiopulmonary Exercise Testing in Patients with Heart Failure

Published on: October 1, 2019

6.2K
Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans
07:26

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans

Published on: October 17, 2018

21.3K
Surgical Placement of Catheters for Long-term Cardiovascular Exercise Testing in Swine
12:37

Surgical Placement of Catheters for Long-term Cardiovascular Exercise Testing in Swine

Published on: February 9, 2016

13.9K

Area of Science:

  • Pulmonology
  • Respiratory Medicine
  • Clinical Diagnostics

Background:

  • Respiratory symptoms are a frequent reason for healthcare visits, significantly impacting resource utilization.
  • Accurate diagnosis of respiratory symptoms is essential for effective patient management but often challenging.
  • Objective assessment tools are crucial for discerning the causes of respiratory issues.

Purpose of the Study:

  • To review key aspects of pulmonary function evaluation.
  • To highlight the indications and contraindications for pulmonary function tests.
  • To explain the interpretation fundamentals and limitations of pulmonary function components.

Main Methods:

  • Review of existing literature and clinical guidelines on pulmonary function testing.
  • Analysis of diagnostic utility and interpretation principles for various pulmonary function tests.
  • Discussion of the practical application and limitations in clinical settings.

Main Results:

  • Pulmonary function tests provide objective data crucial for diagnosing respiratory diseases.
  • Understanding test indications, contraindications, and interpretation is vital for accurate diagnosis.
  • Each component of pulmonary function evaluation has specific limitations that must be considered.

Conclusions:

  • Pulmonary function evaluation is an indispensable tool in the diagnostic workup of respiratory symptoms.
  • Clinicians must be familiar with the proper application and interpretation of these tests.
  • Objective assessment via pulmonary function testing guides effective therapeutic strategies for respiratory conditions.