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Updated: Jan 26, 2026

Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
Published on: April 11, 2018
Evaluation of Planned versus Unplanned Soft-Tissue Sarcoma Resection Using PROMIS Measures
Benjamin K Wilke1, Anna R Cooper1, Ashley K Aratani1
1Division of Orthopaedic Oncology, University of Florida, Gainesville, FL, USA.
Patients undergoing unplanned sarcoma excision followed by resection show similar outcomes to those with planned surgery. Both groups report improved emotional health compared to the general U.S. population using Patient Reported Outcomes Measurement Information System (PROMIS) measures.
Area of Science:
- Oncology
- Surgical Outcomes
- Patient-Reported Outcomes
Background:
- The Patient Reported Outcomes Measurement Information System (PROMIS) enables health comparisons across diverse populations.
- PROMIS facilitates standardized assessment of patient well-being.
Purpose of the Study:
- To compare PROMIS outcomes between patients with planned sarcoma resection versus those with initial unplanned excision followed by definitive oncologic resection.
- To compare these patient groups to the general U.S. population.
Main Methods:
- Eighty-five sarcoma patients were analyzed.
- Patients were categorized into planned resection (67) and unplanned excision (18) groups.
- Follow-up was categorized as early (<12 months) or late (>12 months).
Main Results:
- No significant differences in PROMIS scores were observed between planned resection and unplanned excision groups.
- Both patient groups reported significantly improved emotional health scores compared to the U.S. general population.
Conclusions:
- Unplanned excision followed by definitive oncologic resection yields comparable PROMIS scores to planned resection.
- Surgical approach for sarcoma does not negatively impact patient-reported outcomes as measured by PROMIS.
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