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Transient T3 toxicosis associated with Hashimoto's disease
Sarah Jaroudi1, Meredith Gavin1, Kathryn Boylan1
1Texas Tech University Health Sciences Center, School of MedicineLubbockTexas.
Proceedings (Baylor University. Medical Center)
|April 9, 2019
Summary
Early Hashimoto's disease can cause thyrotoxicosis. This case highlights a rare instance of elevated T3 toxicosis in Hashimoto's disease that resolved spontaneously.
Area of Science:
- Endocrinology
- Thyroidology
Background:
- Hashimoto's disease, an autoimmune thyroiditis, can initially present with thyrotoxicosis (Hashitoxicosis).
- Typical Hashitoxicosis involves elevated free thyroxine (FT4) and suppressed thyroid-stimulating hormone (TSH).
Observation:
- A 27-year-old woman presented with incidentally discovered elevated free triiodothyronine (FT3) levels, normal FT4, and suppressed TSH.
- The patient had positive thyroid peroxidase and thyroglobulin antibodies, with thyroid heterogeneity on ultrasound.
- No treatment was initiated as the condition resolved spontaneously.
Findings:
- This case documents an unusual presentation of T3 toxicosis in the context of Hashimoto's disease.
- Elevated FT3 with normal FT4 and suppressed TSH is a rare manifestation.
Implications:
- This case expands the known clinical spectrum of early Hashimoto's disease presentations.
- Understanding rare thyroid dysfunction patterns is crucial for accurate diagnosis and management.
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