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Updated: Jan 26, 2026

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates
Published on: March 20, 2015
Tape-Imprinted Hierarchical Lotus Seedpod-Like Arrays for Extraordinary Surface-Enhanced Raman Spectroscopy
Yandong Wang1, Mengyuan Zhang1, Lei Feng2
1Institute of Functional Nano and Soft Materials (FUNSOM), Soochow University, Suzhou, 215123, P. R. China.
Abstract:
A novel two-side-activatable high-performance surface-enhanced Raman spectroscopy (SERS) substrate is developed based on the tape-imprinting method. It features 3D full-space-distributed hot spots originating from the hierarchical lotus seedpod-like silver arrays, which offer ultrasensitive, uniform, reproducible, and reliable quantitative measurements with an inherent internal standard. This excellent SERS substrate also holds great promise in practical in situ molecule detection on curved surfaces, such as pesticides on fruit, which is not yet possible with the traditional rigid or flexible material-based SERS counterparts.
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