Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Atomic Spectroscopy: Absorption, Emission, and Fluorescence01:23

Atomic Spectroscopy: Absorption, Emission, and Fluorescence

2.7K
Atomic spectroscopy is a vital tool in elemental analysis, both qualitatively and quantitatively. It can be broadly divided into optical spectroscopy, mass spectroscopy, and X-ray spectroscopy methods. The optical spectroscopic methods are atomic absorption spectroscopy (AAS), atomic emission spectroscopy (AES), and atomic fluorescence spectroscopy (AFS). The first step in all three methods is atomization, where the solid, liquid, or solution-phase samples are converted into gas-phase atoms and...
2.7K
Emission Spectra02:39

Emission Spectra

75.9K
When solids, liquids, or condensed gases are heated sufficiently, they radiate some of the excess energy as light. Photons produced in this manner have a range of energies, and thereby produce a continuous spectrum in which an unbroken series of wavelengths is present.
75.9K
Benzene to 1,4-Cyclohexadiene: Birch Reduction Mechanism01:18

Benzene to 1,4-Cyclohexadiene: Birch Reduction Mechanism

2.6K
Birch reduction uses solvated electrons as reducing agents. The reaction converts benzene to 1,4-cyclohexadiene. The reaction proceeds by the transfer of a single electron to the ring to form a benzene radical anion. This anion is highly basic—it abstracts a proton from the alcohol to form a cyclohexadienyl radical. Another single electron transfer gives the cyclohexadienyl anion. A proton transfer from the alcohol forms 1,4-cyclohexadiene. Since this reduction occurs via radical anion...
2.6K
Phase Diagrams02:39

Phase Diagrams

49.9K
A phase diagram combines plots of pressure versus temperature for the liquid-gas, solid-liquid, and solid-gas phase-transition equilibria of a substance. These diagrams indicate the physical states that exist under specific conditions of pressure and temperature and also provide the pressure dependence of the phase-transition temperatures (melting points, sublimation points, boiling points). Regions or areas labeled solid, liquid, and gas represent single phases, while lines or curves represent...
49.9K
Phase Transitions02:31

Phase Transitions

22.9K
Whether solid, liquid, or gas, a substance's state depends on the order and arrangement of its particles (atoms, molecules, or ions). Particles in the solid pack closely together, generally in a pattern. The particles vibrate about their fixed positions but do not move or squeeze past their neighbors. In liquids, although the particles are closely spaced, they are randomly arranged. The position of the particles are not fixed—that is, they are free to move past their neighbors to...
22.9K
Electrophilic 1,2- and 1,4-Addition of X2 to 1,3-Butadiene01:14

Electrophilic 1,2- and 1,4-Addition of X2 to 1,3-Butadiene

3.5K
Electrophilic addition of halogens to alkenes proceeds via a cyclic halonium ion to form a 1,2-dihalide or a vicinal dihalide.
3.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Gut-Derived Sodium Butyrate Attenuates Liver Fibrosis by Inhibiting Aerobic Glycolysis via the HDAC3/c-Myc Signaling Axis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2026
Same author

The Endothelial Activation and Stress Index (EASIX) at diagnosis is associated with survival in primary central nervous system lymphoma.

British journal of haematology·2026
Same author

AI-Powered Lesion-Level Tumor Growth Inhibition Modeling Improves Model Stability and Prognostic Association With PFS.

CPT: pharmacometrics & systems pharmacology·2026
Same author

Twisted Intramolecular Charge Shuttle (TICS) Enables Ultrafast Ratiometric Sensing and Imaging of Nitrite.

Angewandte Chemie (International ed. in English)·2026
Same author

Fluorescent self-reporting theranostic platforms for tumour therapy: from cytotoxin release monitoring to therapeutic feedback evaluation.

Journal of materials chemistry. B·2026
Same author

Organic Host-Guest Doped Red Room-Temperature Ultralong Afterglow Materials Based on Benzo[a]Carbazole Derivatives.

Chemistry (Weinheim an der Bergstrasse, Germany)·2026

Related Experiment Video

Updated: Jan 26, 2026

Simultaneously Capturing Real-time Images in Two Emission Channels Using a Dual Camera Emission Splitting System: Applications to Cell Adhesion
10:30

Simultaneously Capturing Real-time Images in Two Emission Channels Using a Dual Camera Emission Splitting System: Applications to Cell Adhesion

Published on: September 4, 2013

10.0K

Aggregation-Induced Emission-Active 1,4-Dihydropyridine-Based Dual-Phase Fluorescent Sensor with Multiple Functions.

Yibin Zhou1, Yating Chen1, Chong Duan2

  • 1College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou, 325035, P. R. China.

Chemistry, an Asian Journal
|April 9, 2019
PubMed
Summary

A novel N-2-phenylethyl-substituted 1,4-dihydropyridine derivative (NDHP) functions as a dual-phase fluorescent sensor. This material exhibits aggregation-induced emission, mechanochromism, and selective Hg2+ detection for imaging.

Keywords:
1,4-dihydropyridine derivativesaggregation-induced emissiondual-phase fluorescent sensormercury ion detectionsolid-state stimuli-responsive fluorescent properties

More Related Videos

Design and Use of a Full Flow Sampling System FFS for the Quantification of Methane Emissions
08:18

Design and Use of a Full Flow Sampling System FFS for the Quantification of Methane Emissions

Published on: June 12, 2016

17.3K
Laser-Induced Fluorescence Emission L.I.F.E. as Novel Non-Invasive Tool for In-Situ Measurements of Biomarkers in Cryospheric Habitats
13:38

Laser-Induced Fluorescence Emission L.I.F.E. as Novel Non-Invasive Tool for In-Situ Measurements of Biomarkers in Cryospheric Habitats

Published on: October 26, 2019

8.4K

Related Experiment Videos

Last Updated: Jan 26, 2026

Simultaneously Capturing Real-time Images in Two Emission Channels Using a Dual Camera Emission Splitting System: Applications to Cell Adhesion
10:30

Simultaneously Capturing Real-time Images in Two Emission Channels Using a Dual Camera Emission Splitting System: Applications to Cell Adhesion

Published on: September 4, 2013

10.0K
Design and Use of a Full Flow Sampling System FFS for the Quantification of Methane Emissions
08:18

Design and Use of a Full Flow Sampling System FFS for the Quantification of Methane Emissions

Published on: June 12, 2016

17.3K
Laser-Induced Fluorescence Emission L.I.F.E. as Novel Non-Invasive Tool for In-Situ Measurements of Biomarkers in Cryospheric Habitats
13:38

Laser-Induced Fluorescence Emission L.I.F.E. as Novel Non-Invasive Tool for In-Situ Measurements of Biomarkers in Cryospheric Habitats

Published on: October 26, 2019

8.4K

Area of Science:

  • Materials Science
  • Organic Chemistry
  • Analytical Chemistry

Background:

  • Fluorescent sensors are crucial for detecting analytes and studying cellular processes.
  • Developing multifunctional sensors that operate in both solid and solution phases remains a challenge.

Purpose of the Study:

  • To design and synthesize a novel N-2-phenylethyl-substituted 1,4-dihydropyridine derivative (NDHP) with dual-phase sensing capabilities.
  • To investigate the photophysical properties and applications of NDHP as a fluorescent sensor.

Main Methods:

  • Synthesis of the NDHP derivative.
  • Crystal structure analysis to determine molecular conformation.
  • Photophysical characterization in solid and solution states.
  • Testing for mechanochromism and acid-fumed emission.
  • Evaluation of selective Hg2+ detection and intracellular imaging.

Main Results:

  • NDHP exhibits a twisted conformation leading to aggregation-induced emission and solid-state emission.
  • Reversible mechanochromic properties were observed due to amorphous-crystalline state transitions.
  • Acid-fumed solid-state emission enhancement was achieved via J-aggregation.
  • Selective "turn-on" fluorescence detection of Hg2+ in solution with a low limit of detection (2.7 nm).
  • Successful imaging of intracellular Hg2+ in HeLa cells.

Conclusions:

  • The synthesized NDHP is a versatile fluorescent material with applications in rewritable optical media and logic systems.
  • NDHP serves as an effective sensor for Hg2+ in both solution and biological environments.
  • This work presents a promising strategy for developing multifunctional, dual-phase fluorescent sensors.