Action of Halogenated Compounds on Aspergillus Conidiospores

The fungicidal activity of two halogenated compounds against conidiospores of four Aspergillus strains ( A. flavus and A. sydowi isolated from a poultry farm, A. parasiticus NRRL 2999 and A. niger 29-CCM-A 41) was studied. Accordingly, the sodium salt of a synthetic organic compound derived from trichloroisocyanuric acid and an organic complex of iodine (iodophor) were used at 20°C at their recommended dilution (0.1%). More than 99.9% of the exposed spore population of all strains was inactivated within 30 min of contact with either product. During the first minute of contact, the iodophor solution was more effective than the chlorinated one. Among parameters tested on A. niger conidiospores, a 10°C temperature rise slightly increased antimicrobial activity, which was substantially affected by dilution, the active principle being exhausted when using 0.05% concentration. In addition, organic matter (1% human serum) practically neutralized the fungicidal effect of both compounds, whereas acid pH (5.33) notably increased the antimicrobial capacity of the chlorinated derivative.