Related Experiment Video
Updated: Jan 26, 2026

Pseudofracture: An Acute Peripheral Tissue Trauma Model
Published on: April 18, 2011
Contemporary management and prognosis of great vessels trauma
Szu-An Chen1, Jen-Fu Huang1, Yu-San Tee1
1Department of Traumatology and Emergency Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan.
Insights
Great vessel trauma (GVT) is a rare but lethal injury. Survival depends on injury severity and shock status, with vena caval injuries being a key predictor of mortality.
Area of Science:
- Trauma Surgery
- Vascular Surgery
- Emergency Medicine
Background:
- Great vessel trauma (GVT), involving the aorta or vena cava, presents significant management challenges and high mortality rates.
- Optimal treatment strategies for GVT remain debated within the medical community.
Purpose of the Study:
- To review the incidence, management, and outcomes of GVT.
- To identify prognostic factors and compare treatment results for GVT patients.
Main Methods:
- Retrospective, single-center cohort study of GVT patients from August 2008 to December 2013.
- Data collected included demographics, injury details, treatment choices, hospital stay, and mortality.
- Analysis focused on risks of adverse outcomes and mortality.
Main Results:
- A cohort of 74 patients experienced a 27% mortality rate.
- Prognostic factors for survival included male gender, lower Injury Severity Score (ISS), higher Glasgow Coma Scale (GCS), and higher blood pressure.
- Vena caval injuries were identified as the primary predictor of mortality.
Conclusions:
- GVT is infrequent but carries a high fatality rate.
- Patient survival is linked to injury severity and shock grade.
- Aggressive resuscitation, coordinated surgical expertise, and innovative treatments are crucial for improving outcomes, especially for vena caval injuries.
Background:
Great vessel trauma (GVT), which is defined as trauma to the aorta or vena cava, remains one of the most challenging injuries to treat and has a high mortality rate despite advances in modern medicine. Additionally, the optimal management of GVT is controversial. In this study, we review the incidence, management, and outcome of GVT, identify the current status and prognostic factors of GVT, and compare treatment outcomes.
Methods:
We conducted a retrospective, single-center, cohort study of patients with GVT in a Level I trauma center from August 2008 to December 2013. We retrieved demographic data, physical and imaging findings, injury severity score (ISS), treatment choice, length of hospital stay, and mortality. We analyzed the risks of adverse outcomes and mortality.
Results:
The seventy-four patients in this cohort had a mean age of 41.6 (SD 17.7) years and a high mortality rate of 27%. The prognostic factors of survival with GVT included male gender, lower ISS, higher GCS, higher SBP and DBP and vena caval injuries. We also determined that vena caval injury is the main factor that can predict mortality.
Conclusion:
In conclusion, GVT is relatively rare but often lethal in clinical practice. Patient survival depends on injury severity and the shock status grade. Aggressive resuscitation and treatment play important roles in survival. The coordination of different levels of surgical expertise and the application of novel treatment methods are required to improve clinical outcomes for patients with vena caval injuries.
Related Concept Videos
Contemporary Psychology
Biopsychology
Biopsychology, also known as biological psychology or behavioral neuroscience, focuses on the biological underpinnings of behavior and mental processes. It...
Structure of Blood Vessels
Anatomy of Blood Vessels
Arteries
Arteries circulate oxygenated blood from the heart, except the pulmonary artery, which transports deoxygenated blood to the lungs. Large arteries, such as the aorta,...
Overview of Blood Vessels
Arteries and Arterioles: Arteries are muscular and elastic vessels that primarily carry oxygenated blood from the heart to body tissues, except for the pulmonary artery, which carries deoxygenated blood. They have thick walls to withstand high pressure and contain a layer of muscle tissue, allowing them to expand or contract as...
Development of Blood Vessels
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...
Lymphatic Vessels and Lymph Transport
This one-way system allows fluids, solutes, and even pathogens to enter but prevents their return to the intercellular...

