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Updated: Jan 26, 2026
09:10
Generation of Lymph Node-fat Pad Chimeras for the Study of Lymph Node Stromal Cell Origin
Published on: December 16, 2013
6.4K
Lobectomy for subsegmental lymph node metastasis of unknown origin.
Gaku Yamaguchi1,2, Osamu Uchida1, Shuji Ichinose1
1Department of Respiratory Surgery, Funabashi Municipal Medical Center, Chiba, Japan.
Nagoya Journal of Medical Science
|April 10, 2019
Summary
This case study details a rare instance of intrapulmonary lymph node metastasis of unknown origin. Evanescence of a primary lesion may indicate metastasis, with FDG-PET aiding detection.
Area of Science:
- Oncology
- Radiology
- Thoracic Surgery
Background:
- Lymph node metastasis of unknown primary origin is rare.
- Intrapulmonary lymph node metastasis has not been previously reported.
- Hilar (N1) lymph node metastasis has been documented.
Observation:
- A patient presented with an upper lung nodule on chest radiograph.
- The initial nodule vanished over 4 years, with a new tiny nodule emerging.
- 2-Fluoro-2-deoxy-D-glucose positron-emission tomography (FDG-PET) showed abnormal uptake in the new nodule.
Findings:
- Resection revealed a metastatic subsegmental lymph node.
- No primary lesion was identified.
- The evanescence of the initial lesion suggested metastasis.
Implications:
- This case highlights a novel presentation of intrapulmonary lymph node metastasis.
- FDG-PET is valuable for detecting lymph node metastases and ruling out primary lesions.
- Evanescence of suspicious lesions warrants further investigation for metastasis.
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