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Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
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WITHDRAWN: Interventions for guttate psoriasis
Robert Chalmers1, Teresa O'Sullivan, Caroline M Owen
1The Dermatology Centre, The University of Manchester, Salford Royal NHS Foundation Trust, Stott Lane, Salford, Manchester, UK, M6 8HD.
The Cochrane Database of Systematic Reviews
|April 10, 2019
Summary
Limited evidence exists for guttate psoriasis treatments. A single trial suggests n-3 fatty acid emulsions may benefit guttate psoriasis patients, but more research is needed.
Area of Science:
- Dermatology
- Clinical Trials
- Evidence-Based Medicine
Background:
- Guttate psoriasis is an acute form of psoriasis common in children and young adults.
- Evidence-based guidance for treating guttate psoriasis is scarce in medical literature.
Purpose of the Study:
- To evaluate the effectiveness of various treatments for guttate psoriasis.
Main Methods:
- Searched multiple databases including Cochrane Clinical Trials Register, Medline, and Embase for guttate psoriasis studies.
- Included randomized controlled trials (RCTs) comparing different treatments, excluding antistreptococcal interventions.
- Two reviewers independently assessed trial eligibility and quality.
Main Results:
- Only one small RCT met the inclusion criteria, involving 21 hospitalized patients.
- The trial compared intravenous n-3 fatty acid rich lipid emulsion with a placebo emulsion.
- The n-3 fatty acid preparation showed potential benefit for guttate psoriasis patients.
Conclusions:
- There is insufficient evidence to guide current treatment strategies for acute guttate psoriasis.
- Further studies are needed to compare standard treatments like phototherapy and topical regimens.
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