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Updated: Jan 26, 2026

Activating Autophagy by Aerobic Exercise in Mice
Published on: February 3, 2017
Macropinocytosis and autophagy crosstalk in nutrient scavenging
Oliver Florey1, Michael Overholtzer2
11 Signalling Programme, Babraham Institute , Cambridge CB22 3AT , UK.
Abstract:
Adaptive strategies used by cells to scavenge and recycle essential nutrients are important for survival in nutrient-depleted environments such as cancer tissues. Autophagy and macropinocytosis are two major mechanisms that promote nutrient recycling and scavenging, which share considerable, yet poorly understood, cross-regulation. Here we review recent findings that connect these starvation response mechanisms and discuss the implications of their crosstalk. This article is part of the Theo Murphy meeting issue 'Macropinocytosis'.
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