Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Criteria for Causality: Bradford Hill Criteria - II01:28

Criteria for Causality: Bradford Hill Criteria - II

1.2K
The Bradford Hill criteria serve as guidelines for establishing causative links in epidemiological research. Beyond Strength, Consistency, Specificity, and Temporality, key criteria also include Biological Gradient, Plausibility, Coherence, Experiment, and Analogy. These principles assist scientists in assessing the likelihood of causation in complex biological contexts. Below is a summary of these concepts:
1.2K
Criteria for Causality: Bradford Hill Criteria - I01:30

Criteria for Causality: Bradford Hill Criteria - I

1.1K
The Bradford Hill criteria are a group of principles that provide a framework to determine a causal relationship between a specific factor and a disease. There are nine criteria that are pivotal in assessing causality in epidemiological studies. Here's a closer look at Strength, Consistency, Specificity, and Temporality criteria with definitions and examples:
1.1K
Trial and Error and Algorithm01:12

Trial and Error and Algorithm

403
A problem-solving strategy is a plan of action used to find a solution. Different strategies have distinct action plans. Trial and error involves trying different solutions until one works. For instance, to fix a broken printer, you might check ink levels, ensure the paper tray isn't jammed, and verify the printer's connection to your laptop. This method can be time-consuming but is commonly used. Thomas Edison, for example, used trial and error to find a suitable filament for the light...
403
Yield Criteria for Ductile Materials under Plane Stress01:25

Yield Criteria for Ductile Materials under Plane Stress

505
In designing structural elements and machine parts using ductile materials, it is crucial to ensure that these components withstand applied stresses without yielding. Yielding is initially determined through a tensile test, which evaluates the material's response to uniaxial stress. However, tensile stress is insufficient when components face biaxial or plane stress conditions This condition requires advanced criteria to predict failure.
The Maximum Shearing Stress Criterion, also known as...
505
Criteria for Aromaticity and the Hückel 4n + 2 Rule01:20

Criteria for Aromaticity and the Hückel 4n + 2 Rule

13.0K
Like benzene, cyclobutadiene and cyclooctatetraene are cyclic compounds with alternate single and double bonds. However, their chemical behavior differs from benzene, as they are unstable and not aromatic. So, what are the structural characteristics of unsaturated compounds categorized as aromatic?  
For the first time, Eric Hückel, a German chemical physicist, derived a set of structural features for a compound to be classified as aromatic. This is now known as Hückel’s rule or the 4n +...
13.0K
Optimal Foraging00:48

Optimal Foraging

13.8K
How animals obtain and eat their food is called foraging behavior. Foraging can include searching for plants and hunting for prey and depends on the species and environment.
13.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development of an indirect ELISA for the detection of venezuelan equine encephalitis virus specific antibodies in horses.

PloS one·2026
Same author

Development and Evaluation of a Web-Based App for Adverse Effect Management in Breast Cancer Patients Treated with Oral Targeted Therapy or Chemotherapy: Findings from a Pilot Study.

Current oncology (Toronto, Ont.)·2026
Same author

Pelvic nodes ultra-hypo fractionated versus conventionally fractionated IMRT with HDR brachytherapy in prostate cancer: interim analysis of a collaborative multi-institutional non-inferiority phase 3 trial (PCS-XI, NCT05820633).

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2026
Same author

A Call for a Collaborative Framework for Automation in Adaptive Radiotherapy.

Technology in cancer research & treatment·2026
Same author

Robust external-beam calibration of plastic scintillation detectors and uncertainty analysis for<i>in-vivo</i>dosimetry in HDR brachytherapy.

Physics in medicine and biology·2026
Same author

AAPM task group 317 report: A joint AAPM and ESTRO report on brachytherapy catheter, needle, and applicator tracking technology.

Medical physics·2026
Same journal

Effective contrast-enhanced preprocessing for intracranial artery segmentation in digital subtraction angiography.

Physics in medicine and biology·2026
Same journal

Improving Plan Quality in Adaptive Proton Therapy Using an Interactive Dose Modification Tool.

Physics in medicine and biology·2026
Same journal

Technical Note: Real-Time MLC Control and Latency Measurement Optimization with External Verification.

Physics in medicine and biology·2026
Same journal

Fetus-Specific Hematopoietic Stem Cell Dosimetry Framework for Leukemia-Relevant Target Cells During Prenatal Development.

Physics in medicine and biology·2026
Same journal

Deep learning-based dose prediction to enhance planning efficiency in cervical brachytherapy with hybrid applicators.

Physics in medicine and biology·2026
Same journal

Corrigendum: Referenceless MR thermometry-a comparison of five methods (2017<i>Phys. Med. Biol</i>.<b>62</b>1-16).

Physics in medicine and biology·2026
See all related articles

Related Experiment Video

Updated: Jan 26, 2026

Two Algorithms for High-throughput and Multi-parametric Quantification of Drosophila Neuromuscular Junction Morphology
12:29

Two Algorithms for High-throughput and Multi-parametric Quantification of Drosophila Neuromuscular Junction Morphology

Published on: May 3, 2017

11.0K

A GPU-based multi-criteria optimization algorithm for HDR brachytherapy.

Cédric Bélanger1,2,3, Songye Cui1,2,3, Yunzhi Ma2

  • 1Department of Physics, Engineering Physics and Optics and Cancer Research Center, Université Laval, Quebec City, QC, G1V 0A6, Canada.

Physics in Medicine and Biology
|April 11, 2019
PubMed
Summary
This summary is machine-generated.

This study introduces a GPU-based multi-criteria optimization (gMCO) algorithm for high-dose-rate (HDR) prostate brachytherapy planning. The gMCO algorithm significantly improves treatment plan quality and reduces planning time compared to traditional methods.

More Related Videos

Management of Respiratory Motion Artefacts in 18F-fluorodeoxyglucose Positron Emission Tomography using an Amplitude-Based Optimal Respiratory Gating Algorithm
06:53

Management of Respiratory Motion Artefacts in 18F-fluorodeoxyglucose Positron Emission Tomography using an Amplitude-Based Optimal Respiratory Gating Algorithm

Published on: July 23, 2020

6.1K
Area-based Image Analysis Algorithm for Quantification of Macrophage-fibroblast Cocultures
07:05

Area-based Image Analysis Algorithm for Quantification of Macrophage-fibroblast Cocultures

Published on: February 15, 2022

2.9K

Related Experiment Videos

Last Updated: Jan 26, 2026

Two Algorithms for High-throughput and Multi-parametric Quantification of Drosophila Neuromuscular Junction Morphology
12:29

Two Algorithms for High-throughput and Multi-parametric Quantification of Drosophila Neuromuscular Junction Morphology

Published on: May 3, 2017

11.0K
Management of Respiratory Motion Artefacts in 18F-fluorodeoxyglucose Positron Emission Tomography using an Amplitude-Based Optimal Respiratory Gating Algorithm
06:53

Management of Respiratory Motion Artefacts in 18F-fluorodeoxyglucose Positron Emission Tomography using an Amplitude-Based Optimal Respiratory Gating Algorithm

Published on: July 23, 2020

6.1K
Area-based Image Analysis Algorithm for Quantification of Macrophage-fibroblast Cocultures
07:05

Area-based Image Analysis Algorithm for Quantification of Macrophage-fibroblast Cocultures

Published on: February 15, 2022

2.9K

Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Computational Optimization

Background:

  • High-dose-rate (HDR) brachytherapy planning for prostate cancer currently requires manual adjustment of objective functions.
  • This manual tuning is time-consuming and can lead to suboptimal, case-specific treatment plans.

Purpose of the Study:

  • To develop and evaluate a patient-specific inverse planning algorithm for HDR prostate brachytherapy.
  • To facilitate the creation of high-quality, valid treatment plans more efficiently.

Main Methods:

  • Implementation of two GPU-based optimization engines: simulated annealing (gSA) and quasi-Newton (gL-BFGS).
  • Development of a GPU-based multi-criteria optimization (gMCO) algorithm using the faster gL-BFGS engine.
  • Comparison of gMCO plans against physician-approved clinical plans in a large dataset (462 cases).

Main Results:

  • The gL-BFGS engine demonstrated up to 67 times faster computation than gSA, with equivalent optimization outcomes.
  • gMCO plans showed a higher rate of clinical validity (99.8% vs. 92.6%) and superior target coverage (>95% in 89.6% vs. 62.3% of cases).
  • The gMCO algorithm generated 1000 Pareto optimal plans in a mean of 9.4 seconds, significantly reducing planning time.

Conclusions:

  • The gL-BFGS-powered gMCO algorithm offers an ultra-fast and robust solution for HDR prostate brachytherapy planning.
  • This approach enables the creation of plan pools with diverse trade-offs, improving treatment plan quality and drastically reducing planning time.