Case-control study of the low intensive autism-specific early behavioral intervention A-FFIP: Outcome after one year

Janina Kitzerow1, Karoline Teufel1, Katrin Jensen2

  • 1Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Autism Research and Intervention Center of Excellence Frankfurt, Goethe University Frankfurt am Main, Germany.

Insights

The Frankfurt Early Intervention Program (A-FFIP) showed promising results for children with autism spectrum disorder (ASD), improving cognitive development and reducing psychopathology. Further research is needed to confirm the efficacy of this naturalistic developmental behavioral intervention (NDBI).

Area of Science:

  • Child Psychology
  • Developmental Neuroscience
  • Behavioral Therapy

Background:

  • Early intervention for autism spectrum disorder (ASD) increasingly utilizes naturalistic developmental behavioral interventions (NDBI).
  • The Frankfurt Early Intervention Program (A-FFIP) applies NDBI principles in a low-intensity, 2-hour/week format for preschool-aged children with ASD.

Purpose of the Study:

  • To evaluate the effect sizes of the A-FFIP on autistic symptoms, comorbid behavioral problems, and IQ after one year.
  • To compare the outcomes of A-FFIP intervention with a treatment-as-usual control group.

Main Methods:

  • A case-control study involving 20 children with ASD in the intervention group and 20 in the control group, matched for age.
  • Outcome measures included the ADOS severity score, Child Behavior Checklist, and cognitive development assessments.

Main Results:

  • The A-FFIP group demonstrated a trend towards greater improvement in autistic symptoms compared to the control group.
  • Significant improvements were observed in cognitive development and global psychopathology in the A-FFIP group.
  • Effect sizes (η 2 ) were reported for changes in autistic symptoms (.087), cognitive development (.206), and global psychopathology (.144).

Conclusions:

  • The A-FFIP shows potential efficacy in improving cognitive development and reducing psychopathology in young children with ASD.
  • The findings suggest that low-intensity NDBI can be effective.
  • Larger, randomized controlled trials are recommended to definitively establish the efficacy of A-FFIP.

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