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Case-control study of the low intensive autism-specific early behavioral intervention A-FFIP: Outcome after one year
Janina Kitzerow1, Karoline Teufel1, Katrin Jensen2
1Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Autism Research and Intervention Center of Excellence Frankfurt, Goethe University Frankfurt am Main, Germany.
Insights
The Frankfurt Early Intervention Program (A-FFIP) showed promising results for children with autism spectrum disorder (ASD), improving cognitive development and reducing psychopathology. Further research is needed to confirm the efficacy of this naturalistic developmental behavioral intervention (NDBI).
Area of Science:
- Child Psychology
- Developmental Neuroscience
- Behavioral Therapy
Background:
- Early intervention for autism spectrum disorder (ASD) increasingly utilizes naturalistic developmental behavioral interventions (NDBI).
- The Frankfurt Early Intervention Program (A-FFIP) applies NDBI principles in a low-intensity, 2-hour/week format for preschool-aged children with ASD.
Purpose of the Study:
- To evaluate the effect sizes of the A-FFIP on autistic symptoms, comorbid behavioral problems, and IQ after one year.
- To compare the outcomes of A-FFIP intervention with a treatment-as-usual control group.
Main Methods:
- A case-control study involving 20 children with ASD in the intervention group and 20 in the control group, matched for age.
- Outcome measures included the ADOS severity score, Child Behavior Checklist, and cognitive development assessments.
Main Results:
- The A-FFIP group demonstrated a trend towards greater improvement in autistic symptoms compared to the control group.
- Significant improvements were observed in cognitive development and global psychopathology in the A-FFIP group.
- Effect sizes (η 2 ) were reported for changes in autistic symptoms (.087), cognitive development (.206), and global psychopathology (.144).
Conclusions:
- The A-FFIP shows potential efficacy in improving cognitive development and reducing psychopathology in young children with ASD.
- The findings suggest that low-intensity NDBI can be effective.
- Larger, randomized controlled trials are recommended to definitively establish the efficacy of A-FFIP.
Abstract:
Abstracts: Objective: In current international research, early intervention in children with autism-spectrum disorder (ASD) focuses on naturalistic developmental behavioral interventions (NDBI). The manualized Frankfurt Early Intervention Program for preschool-aged children with ASD (A-FFIP) implements NDBI principles within a low-intensity approach of 2 h intervention/week. The present case-control study established effect sizes of change in autistic symptoms, comorbid behavioral problems as well as IQ after one year. Methodology: An intervention group (N = 20; age: 3.4-7.9 years) and a treatment-as-usual control group (N = 20; age: 3.2-7.3 years) of children with ASD were matched for developmental and chronological age. The outcome measures used were the ADOS severity score, the Child Behavior Checklist, and cognitive development. Results: After one year, the A-FFIP group showed a trend towards greater improvement in autistic symptoms (η2 = .087 [95 %-CI: .000-.159]) and significantly greater improvements in cognitive development (η2 = .206 [CI: .012-.252]) and global psychopathology (η2 = .144 [CI: .001-.205]) compared to the control group. Conclusion: The efficacy of A-FFIP should be established in a larger, sufficiently powered, randomized controlled study.
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