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Related Concept Videos

Surveys02:16

Surveys

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Often, psychologists develop surveys as a means of gathering data. Surveys are lists of questions to be answered by research participants, and can be delivered as paper-and-pencil questionnaires, administered electronically, or conducted verbally. Generally, the survey itself can be completed in a short time, and the ease of administering a survey makes it easy to collect data from a large number of people.
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Introduction to Surveying, Plane Surveying and Geodetic Surveys01:27

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Surveying is the art and science of mapping the earth's surface. It involves measuring distances, angles in horizontal or vertical directions, and levels to understand the shape and size of land features. Surveying techniques are essential for various tasks, such as identifying the levels of a land area with reference to a specific point, and mapping undulations and water bodies.There are two main types of surveying: plane surveys and geodetic surveys. Plane surveys assume the earth is flat,...
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Surveys are essential for marking property boundaries near water bodies. Different types of surveys are defined, each with its own function. Land surveys mark the property boundaries, while route surveys determine the position of properties on nearby highways. Topographic surveys create maps by capturing the three-dimensional features of the land. Hydrographic surveys focus on the shapes of underwater areas and the movement of streams through the properties. Mine surveys determine the relative...
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Survey Safety01:28

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Surveying near highways, rough terrain, or power lines involves significant risks. Working along highways is particularly dangerous and requires the use of warning signs and flagmen. It is safest to avoid working directly on roads and use offsets whenever possible. When highway work is unavoidable, it must follow all safety guidelines. Surveyors should wear bright clothing, such as orange reflective vests, to ensure visibility to motorists, coworkers, and hunters. In construction zones, wearing...
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Errors and Mistakes in Surveying01:19

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Errors and mistakes in surveying refer to inaccuracies in measurements and data recording. The errors are deviations from the actual value caused by human sensory limitations, equipment flaws, or environmental effects. These errors are typically unintentional and can result from the inherent imperfections in the instruments used, atmospheric conditions, or the observer’s inability to perceive exact measurements. On the other hand, mistakes are caused by the surveyor's lack of...
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Cardiac Output II: Effect of Stroke Volume on Cardiac Output01:22

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Cardiac output (CO), the amount of blood the heart pumps per minute, is a parameter in cardiovascular physiology determined by stroke volume and heart rate. Stroke volume, the amount of blood pushed from one of the ventricles per heartbeat, is influenced by preload, afterload, and contractility.
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Related Experiment Video

Updated: Jan 26, 2026

Methods for Image-based Surveys of Benthic Macroinvertebrates and Their Habitat Exemplified by the Drop Camera Survey for the Atlantic Sea Scallop
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Microsampling for quantitative bioanalysis, an industry update: output from an AAPS/EBF survey.

Shefali R Patel1, Peter Bryan2, Neil Spooner3

  • 1DMPK Department, Discovery Sciences, Janssen Research & Development, LLC, 1400 McKean Road, Springhouse, PA 19477, USA.

Bioanalysis
|April 12, 2019
PubMed
Summary

Microsampling technologies are increasingly used in drug development, especially for nonclinical studies. Dried blood microsampling is preferred for clinical applications, enabling challenging sample collection and richer data.

Keywords:
AAPSDBSEBFmicrosampling surveyquantitative bioanalysis

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Area of Science:

  • Drug development
  • Bioanalytical sciences
  • Pharmacokinetics

Background:

  • Growing interest in microsampling technologies for drug development.
  • Microsampling offers potential benefits for sample collection and data acquisition.
  • Industry-wide adoption is increasing but not yet universal.

Purpose of the Study:

  • To survey current practices and adoption trends of microsampling technologies.
  • To understand the extent of microsampling implementation across different study types.
  • To identify preferred microsampling methods in clinical settings.

Main Methods:

  • Survey conducted among members of the AAPS bioanalytical community microsampling subgroup and the European Bioanalysis Forum.
  • Responses gathered from 39 individual organizations.
  • Analysis of current practices and adoption rates of microsampling.

Main Results:

  • Microsampling implementation is becoming increasingly common, particularly in nonclinical studies.
  • A notable number of organizations have submitted microsampling data in regulatory filings.
  • Dried blood microsampling is the predominant approach for clinical studies.

Conclusions:

  • Microsampling technologies are gaining traction in drug development, with varied adoption rates.
  • Nonclinical and non-regulatory studies show higher microsampling adoption.
  • Dried blood microsampling is favored in clinical settings for feasibility and data richness.