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Updated: Jan 26, 2026

Retroductal Nanoparticle Injection to the Murine Submandibular Gland
Published on: May 3, 2018
Metastasis of submandibular gland carcinoma to the toe bone: a case report
1Department of Orthopedics Surgery, Hebei Medical University Fourth Affiliated Hospital and Hebei Provincial Tumor Hospital, 12 Health Road, Shijiazhuang, Hebei 050011, PR China.
Abstract:
Adenoid cystic carcinoma (ACC) is rare. One of its characteristics is a high rate of distant metastasis, and the most common site is the lungs, followed by the brain and liver. Bony metastases account for up to 1.96% of cases only, however, and metastasis from the blood to the bones of distal limbs is rare. We report a 62-year-old woman who presented with pain caused by bony metastases as the first symptom eight years after being diagnosed with submandibular ACC. Although such cases are rare, they indicate that when patients who have had cancer visit the hospital with other symptoms, clinicians should make sure to rule out metastasis.
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