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Published on: August 11, 2015
Pointwise Encoding Time Reduction with Radial Acquisition with Subtraction-Based MRA during the Follow-Up of
Background And Purpose:
Time-of-flight MR angiography, though widely used after coil embolization, is associated with limitations owing to magnetic susceptibility and radiofrequency shielding following stent-assisted coil embolization. We evaluated the pointwise encoding time reduction with radial acquisition (PETRA) sequence in subtraction-based MRA (qMRA) using an ultrashort TE relative to TOF-MRA during the follow-up of stent-assisted coil embolization for anterior circulation aneurysms.
Materials And Methods:
Twenty-five patients (3 men and 22 women; mean age, 59.1 ± 14.0 years) underwent stent-assisted coil embolization for anterior circulation aneurysms and were retrospectively evaluated using TOF-MRA and PETRA qMRA data from the same follow-up session. Two neuroradiologists independently reviewed both MRA findings and subjectively graded flow within the stents (relative to the latest DSA findings) and occlusion status (complete occlusion or neck/aneurysm remnant). Interobserver and intermodality agreement for TOF-MRA and PETRA qMRA were evaluated.
Results:
The mean score for flow visualization within the stents was significantly higher in PETRA qMRA than in TOF-MRA (P < .001 for both observers), and good interobserver agreement was reported (κ = 0.63). The aneurysm occlusion status of PETRA qMRA (observer 1, 92.0%; observer 2, 88.0%) was more consistent with DSA than with TOF-MRA (observer 1, 76.0%; observer 2, 80.0%), and there was a better intermodality agreement between DSA and PETRA qMRA than between DSA and TOF-MRA.
Conclusions:
These findings indicate that PETRA qMRA is a useful follow-up technique for patients who have undergone stent-assisted coil embolization for anterior circulation aneurysms.
Insights
Pointwise encoding time reduction with radial acquisition (PETRA) subtraction-based MRA offers superior visualization of stent-assisted coil embolization follow-up compared to time-of-flight MRA. PETRA qMRA provides more accurate assessment of aneurysm occlusion status.
Area of Science:
- Neuroradiology
- Medical Imaging
- Cardiovascular Interventions
Background:
- Time-of-flight MR angiography (TOF-MRA) has limitations for evaluating stent-assisted coil embolization due to magnetic susceptibility and radiofrequency shielding.
- Stent-assisted coil embolization is a common treatment for anterior circulation aneurysms.
Purpose of the Study:
- To evaluate the efficacy of the pointwise encoding time reduction with radial acquisition (PETRA) sequence in subtraction-based MRA (qMRA) for follow-up after stent-assisted coil embolization.
- To compare PETRA qMRA with TOF-MRA in assessing stent patency and aneurysm occlusion.
Main Methods:
- Retrospective analysis of 25 patients who underwent stent-assisted coil embolization for anterior circulation aneurysms.
- Comparison of TOF-MRA and PETRA qMRA data from the same follow-up session.
- Independent review by two neuroradiologists assessing stent flow and aneurysm occlusion status, with comparison to digital subtraction angiography (DSA).
Main Results:
- PETRA qMRA demonstrated significantly higher scores for flow visualization within stents compared to TOF-MRA (P < .001).
- Aneurysm occlusion status assessment by PETRA qMRA showed better consistency with DSA than TOF-MRA.
- Improved intermodality agreement was observed between DSA and PETRA qMRA compared to DSA and TOF-MRA.
Conclusions:
- PETRA qMRA is a valuable follow-up imaging technique for patients treated with stent-assisted coil embolization for anterior circulation aneurysms.
- PETRA qMRA offers improved visualization and more accurate assessment of treatment outcomes compared to TOF-MRA.
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