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Updated: Jan 26, 2026

Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
Burden, access and disparities in kidney disease
Deidra C Crews1,2,3, Aminu K Bello4, Gamal Saadi5
1Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Kidney disease affects over 750 million people globally, with significant disparities in detection and treatment due to socio-economic factors. Strengthening global kidney care infrastructure is crucial for early detection, management, and equitable access to therapies.
Area of Science:
- Public Health
- Nephrology
- Global Health Disparities
Background:
- Kidney disease is a major global health issue impacting over 750 million individuals worldwide.
- Significant disparities exist in kidney disease burden, detection, and treatment influenced by socio-economic, cultural, and political factors.
- Limited global capacity for prevention and management of kidney disease is evident in many countries.
Purpose of the Study:
- To raise awareness of kidney disease and its global burden.
- To highlight disparities in kidney disease care and global capacity for prevention and management.
- To advocate for improved kidney care infrastructure and pragmatic approaches to renal replacement therapies.
Main Methods:
- Review of global kidney disease burden and care provision.
- Analysis of disparities in detection, treatment, and access to healthcare.
- Examination of existing infrastructure for kidney care services.
Main Results:
- Many countries lack essential diagnostics, trained nephrology workforce, and universal primary healthcare access.
- Access to renal replacement therapies is limited in numerous global settings.
- Significant gaps exist in early detection and management of acute kidney injury and chronic kidney disease.
Conclusions:
- Strengthening basic kidney care infrastructure is essential for early detection and management of kidney disease.
- Pragmatic approaches to renal replacement therapies are needed globally.
- Achieving kidney health equity requires understanding country-specific needs and focusing on feasible interventions within universal health coverage goals.
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Chronic Kidney Disease I: Introduction
Chronic Kidney Disease II: Clinical Manifestations
Chronic Kidney Disease III: Interprofessional Care
Chronic Kidney Disease IV: Nursing Management
Kidney Structure
External Anatomy of the Kidney
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...

