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Related Concept Videos

Irritable Bowel Syndrome I: Introduction01:17

Irritable Bowel Syndrome I: Introduction

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Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
954
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
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Inflammatory Bowel Disease II: Crohn's Disease01:30

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Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
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Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

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Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Inflammatory Bowel Disease IV: Pharmacological Management01:29

Inflammatory Bowel Disease IV: Pharmacological Management

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Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
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Small Bowel Transplantation In Mice
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[Preoperative bowel conditioning].

A-K Eichelmann1, A Pascher2

  • 1Klinik für Allgemein‑, Viszeral- und Transplantationschirurgie, Universitätsklinikum Münster, Albert-Schweitzer-Campus 1, Gebäude W1, 48149, Münster, Deutschland.

Der Chirurg; Zeitschrift Fur Alle Gebiete Der Operativen Medizen
|April 13, 2019
PubMed
Summary

Preoperative bowel conditioning effectively reduces infectious complications after gastrointestinal surgery. Combining mechanical bowel preparation with oral antibiotics or using dietary supplements to stabilize gut flora are promising strategies.

Keywords:
ImmunonutritionIntestinal microbiomeMechanical bowel preparationMetabolic conditioningOral antibiotics

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Area of Science:

  • Gastroenterology
  • Surgical Oncology
  • Microbiome Research

Background:

  • Gastrointestinal surgery carries significant morbidity, with the intestinal microbiome playing a crucial role in infectious complications.
  • Current strategies to modulate gut flora include mechanical bowel preparation (MBP), oral antibiotics, fasting, and dietary supplements.

Purpose of the Study:

  • To review the existing literature on the impact of preoperative bowel conditioning on postoperative morbidity.

Main Methods:

  • A comprehensive literature search was conducted.
  • Emphasis was placed on recent meta-analyses to synthesize findings.

Main Results:

  • Bowel conditioning has been shown to reduce postoperative infectious complications.
  • Mechanical bowel preparation combined with oral antibiotics demonstrates efficacy.
  • Dietary supplements for intestinal flora stabilization are promising.

Conclusions:

  • Preoperative bowel conditioning is vital for minimizing infectious complications post-surgery.
  • Mechanical bowel preparation alone, without antibiotics, is not recommended for routine clinical practice.
  • Addressing malnutrition and stabilizing the gut microbiome are key therapeutic goals.