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Updated: Jan 26, 2026

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions
Published on: November 30, 2022
NNB-Type Tridentate Boryl Ligands Enabling a Highly Active Iridium Catalyst for C⁻H Borylation
Siyi Ding1, Linghua Wang2, Zongcheng Miao3
1Key Laboratory of Organic Polymer Photoelectric Materials, School of Science, Xijing University, Xi'an 710123, China. dingsiyi2009@163.com.
Abstract:
Boryl ligands play a very important role in catalysis because of their very high electron-donating property. In this paper, NNB-type boryl anions were designed as tridentate ligands to promote aryl C-H borylation. In combination with [IrCl(COD)]₂, they generate a highly active catalyst for a broad range of (hetero)arene substrates, including highly electron-rich and/or sterically hindered ones. This work provides a new NNB-type tridentate boryl ligand to support homogeneous organometallic catalysis.
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