Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pulmonary perfusion in HFV: a potential hazard?

Z Kalenda, O van der Vlist, C A Tulleken

    Acta Anaesthesiologica Belgica
    |January 1, 1986
    PubMed
    Summary

    Accurate end-tidal carbon dioxide (ETCO2) measurement during high-frequency ventilation (HFV) is possible with a new method. This technique helps prevent complications by analyzing capnogram patterns related to heart rate and ventilator rate interactions.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Dynamic magnetic resonance imaging and spectroscopie of experimental brain injury.

    Acta neuropsychiatrica·2016
    Same author

    Towards sutureless non-occlusive cerebral revascularization.

    Journal of neurosurgical sciences·2011
    Same author

    Experimentally induced autonomic neuropathy: beneficial effect of a systemic ACTH4-9 analogue on oculomotor nerve regeneration.

    Restorative neurology and neuroscience·2011
    Same author

    Laser-assisted bypass of the internal carotid artery prior to treatment of an extensive angiofibroma.

    Skull base surgery·2006
    Same author

    The ELANA technique: high flow revascularization of the brain.

    Acta neurochirurgica. Supplement·2005
    Same author

    An MKM-mounted instrument holder for frameless point-stereotactic procedures: a phantom-based accuracy evaluation.

    Journal of neurosurgery·2002

    Area of Science:

    • Critical Care Medicine
    • Respiratory Physiology
    • Biomedical Engineering

    Background:

    • Capnography during high-frequency ventilation (HFV) typically measures washout difference (WOD), not end-tidal carbon dioxide (ETCO2).
    • Continuous, instantaneous ETCO2 monitoring is crucial for patient safety during HFV.
    • Interactions between heart rate (HR) and ventilator rate (VR) can create complex capnographic patterns.

    Purpose of the Study:

    • To describe a method for accurate ETCO2 measurement during HFV.
    • To analyze capnographic patterns arising from HR-VR interactions.
    • To demonstrate how capnography can prevent adverse events during HFV.

    Main Methods:

    • Utilized a specialized device and low-flow sidestream capnography for ETCO2 measurement during HFV.
    • Employed an oscillator model with frequencies representing HR and VR to simulate capnographic patterns.
    • Analyzed interference patterns between HR and VR frequencies and their relation to alveolar capillary flow.

    Main Results:

    • Developed a method for accurate ETCO2 measurement during HFV.
    • Observed periodical falls in WOD when HR approached VR or its harmonics, correlating with increased pulmonary artery pressure (PAP), right ventricular pressure (RVP), and central venous pressure (CVP).
    • The oscillator model demonstrated how HR/VR interactions create variable "zero or near-zero zones" affecting alveolar capillary flow, which can be interpreted and clinically managed.

    Conclusions:

    • Continuous ETCO2 monitoring during HFV is feasible and clinically important.
    • Understanding HR/VR interactions through capnography allows for the interpretation and prevention of adverse hemodynamic and respiratory events.
    • Capnographic monitoring provides a valuable tool for optimizing HFV settings and improving patient outcomes.

    Related Experiment Videos