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In Vitro Disassembly of Influenza A Virus Capsids by Gradient Centrifugation
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Putting a New Spin on It: Gradient Centrifugation for Analytical and Preparative Applications
Andreas Spinnrock1, Helmut Cölfen1
1Physical Chemistry, University of Konstanz, Universitätsstrasse 10, Box 714, 78457, Konstanz, Germany.
Chemistry (Weinheim an Der Bergstrasse, Germany)
|April 14, 2019
Summary
Gradient centrifugation offers versatile applications in science and engineering for separating molecules and particles. This technique generates property gradients for advanced analysis, material production, and controlled polymerizations.
Area of Science:
- Chemistry
- Biology
- Materials Science
- Engineering
Background:
- Gradient centrifugation is a key technique with broad applications.
- Its potential extends beyond traditional molecule and particle separation.
Purpose of the Study:
- To present selected examples of gradient centrifugation.
- To discuss developments, applications, potential, and limitations.
- To analyze future trends for academic and industrial use.
Main Methods:
- Centrifugation is used to generate gradients of physical and/or chemical properties.
- These gradients are then utilized for specific applications.
Main Results:
- Demonstrated diverse applications including particle analysis, separation, and preparative uses.
- Highlighted the creation of gradient materials and controlled polymerizations.
Conclusions:
- Gradient centrifugation has significant potential in various scientific fields.
- Future trends indicate relevance for both academic research and industrial applications.
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