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Author Spotlight: Enhancing Coronary Artery Revascularization
Published on: September 15, 2023
[Mid-term multi-center outcomes of bilateral radial artery as conduits in coronary artery bypass grafting]
X J Chen1, B S Zheng2, Y Zhang3
1Department of Cardiac Surgery, Wuhan First Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Insights
Bilateral radial artery (BRA) grafts are safe and effective for coronary artery bypass grafting (CABG), showing excellent mid-term patency and survival rates. This study highlights BRA as a viable option for total arterial revascularization in CABG patients.
Area of Science:
- Cardiovascular Surgery
- Vascular Grafting
- Cardiac Surgery Outcomes
Background:
- Coronary artery bypass grafting (CABG) is a standard treatment for severe coronary artery disease.
- The use of arterial grafts, such as bilateral radial artery (BRA) grafts, is increasingly explored for improved long-term outcomes.
- Evaluating the mid-term efficacy and safety of BRA grafts in CABG is crucial for clinical practice.
Purpose of the Study:
- To assess the mid-term clinical outcomes of patients undergoing CABG using bilateral radial artery (BRA) grafts.
- To evaluate the safety, graft patency, and survival rates associated with BRA grafts in a multi-center cohort.
- To determine the feasibility of BRA grafts for achieving total arterial revascularization in CABG.
Main Methods:
- Retrospective analysis of perioperative and follow-up data from 211 patients who received BRA grafts for CABG across multiple centers in China.
- Data collection included patient demographics, disease severity, comorbidities, surgical procedures, complications, and graft patency via coronary CT angiography (CTA).
- Follow-up duration ranged from 3 to 59 months, assessing clinical events, survival rates, and changes in left ventricular ejection fraction.
Main Results:
- No operation-related deaths occurred; the cumulative survival rate was 100% at 1 year and 99.53% at 3 years.
- Coronary CT angiography showed all grafts were patent in 132 patients at a mean follow-up of 21.5 months.
- Left ventricular ejection fraction significantly improved post-operation (47.1% to 61.0%, P=0.017), with low rates of major complications.
Conclusions:
- Bilateral radial artery (BRA) grafts are a safe arterial conduit for CABG.
- BRA grafts facilitate total arterial revascularization and demonstrate favorable mid-term clinical results.
- The study supports the use of BRA grafts for improved patient outcomes in CABG surgery.
Abstract:
Objective: To evaluate the mid-term outcomes of bilateral radial artery (BRA) grafts in coronary artery bypass grafting (CABG). Methods: All perioperative medical records and follow-up results of CABG with BRA grafts in multi-centers of China were analyzed retrospectively. Results: A total of 211 patients (170 males and 41 females) underwent CABG grafting with BRA conduits between August 2013 and September 2018, with a mean age of (56.5±9.7) years old (rang 41 to 73 years). There were 161 cases of triple-vessel disease and 50 cases of two-vessel disease. Ninety patients had diabetes mellitus (DM), 35 patients with peripheral vascular disease, 4 patients with chronic obstructive pulmonary disease and 11 with heart valve disease. Two patients underwent off-pump CABG and 209 patients accepted on-pump CABG with commitment valve surgery. There were 210 cases of total arterial revascularization and 161 cases using left thoracic artery conduits, with a graft number of 2-4 (2.7±0.9). No operation-related death occurred, atrial fibrillation happened in 12 patients, hemothorax in 7 cases, and forearm hematoma in one case, hypoxemia in 13 cases and pneumonia in one case. The duration of mechanical ventilation was (8.3±4.7) hours and the mean hospital length of stay was (7.1±2.9) days. Follow-up was completed in 191 patients (90.52%) with a duration of 3-59 (35.5±9.3) months. The mean left ventricular ejection fraction at 3 months after operation was significantly improved, compared to that of the pre-operation (61.0%±7.2% vs 47.1%±5.3%, P=0.017). All patients survived, except that one died from brain injury. No major cardiac events occurred, with a cumulative survival rate of 100% at 1 year and 99.53% at 3 year after operation, respectively. It was showed in coronary CT angiography (CTA) examination that all grafts in 132 patients were patent at the mean follow-up duration of (21.5±6.4) months. Conclusions: BRA grafts as arterial conduit in CABG are proved to be safe, easy for total arterial revascularization and have good mid-term clinical results.
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