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Updated: Jan 26, 2026

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
Published on: December 11, 2017
Valve-sparing aortic root replacement in children: Outcomes from 100 consecutive cases
Charles D Fraser1, Rui Han Liu1, Xun Zhou1
1Division of Cardiac Surgery, The Johns Hopkins Hospital, Baltimore, Md.
Insights
Valve-sparing root replacement is a safe and effective option for pediatric aortic root aneurysms. The reimplantation technique is preferred, though late aortic insufficiency and pseudoaneurysms require monitoring.
Area of Science:
- Cardiovascular Surgery
- Pediatric Cardiology
- Aortic Disease
Background:
- Aortic root aneurysms in children often necessitate surgical intervention.
- Valve-sparing root replacement (VSRR) offers an alternative to traditional prostheses.
- Limited data exist on long-term outcomes of VSRR in pediatric populations.
Purpose of the Study:
- To evaluate the safety and efficacy of VSRR in pediatric patients.
- To compare outcomes between different VSRR techniques.
- To identify risk factors for complications and reinterventions.
Main Methods:
- Retrospective review of 100 consecutive pediatric VSRR procedures from 1997-2017.
- Analysis of echocardiographic and clinical data.
- Primary endpoint: mortality; Secondary endpoints: complications, reinterventions, valvular dysfunction.
Main Results:
- Median age was 13.6 years; common diagnoses included Marfan and Loeys-Dietz syndromes.
- Perioperative mortality was 2%. Late reinterventions were needed for pseudoaneurysms in 6% of patients.
- Reimplantation procedures showed significantly lower rates of late valve replacement compared to remodeling (5.9% vs. 33.3%).
Conclusions:
- VSRR is a safe and effective treatment for pediatric aortic root aneurysms.
- The reimplantation technique is associated with better long-term valve outcomes.
- Late aortic insufficiency and pseudoaneurysm formation are potential complications requiring vigilance.
Objective:
Valve-sparing root replacement is an attractive alternative to composite mechanical or biologic prostheses for aortic root aneurysms in children. Data on outcomes in pediatric patients are limited. We present our institutional experience with 100 consecutive pediatric valve-sparing aortic root procedures.
Methods:
All children who underwent valve-sparing root replacement at our institution from May 1997 to August 2017 were identified, and echocardiographic and clinical data were reviewed. The primary end point was mortality, and secondary end points included complications, further interventions, and subsequent valvular dysfunction.
Results:
Median age at operation was 13.6 years (interquartile range, 9.42-15.9); 51 patients (51%) had Marfan syndrome, and 39 patients (39%) had Loeys-Dietz syndrome. Mean preoperative maximum sinus diameter was 4.4 ± 0.71 cm (z score 7.3 [5.7-9.3]). Most patients (n = 80, 80%) underwent reimplantation procedures with a Valsalva graft. Four patients (4%) underwent David I reimplantation with a straight-tube graft, 13 patients (13%) underwent a Yacoub remodeling procedure, and 3 patients (3%) underwent a Florida sleeve procedure. Perioperative valve-sparing root replacement mortality was 2% (n = 2). Six patients required late reintervention for development of pseudoaneurysms. Eight patients underwent additional aortic surgery. Average time to reoperation was 7.23 ± 4.56 years. Of the 84 patients undergoing a reimplantation procedure, 5 (5.9%) underwent late valve replacement versus 5 (33.3%) of the 15 patients who received a remodeling procedure (P = .001).
Conclusions:
Valve-sparing root replacement is a safe and effective option for children with aortic root aneurysms in children. The reimplantation procedure is preferred. Late aortic insufficiency and pseudoaneurysm formation remain late concerns.
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