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Author Spotlight: Identifying Compensatory Pathways in Malaria Parasites Containing Hypomorphic Allele of Essential Protein Kinases
Published on: November 22, 2024
[Current situation of malaria in the world]
Bruno Pradines1, Marie-Gladys Robert2
1Unité de parasitologie et entomologie, département de microbiologie et de maladies infectieuses, Institut de recherche biomédicale des armées, Marseille, France. Centre national de référence du paludisme, Institut de recherche biomédicale des armées, IHU Méditerranée Infection, Marseille, France.
Abstract:
Current situation of malaria in the world. In 2016, 216 million indigenous malaria cases were estimated in the world. Most of them were in Africa -90%-, followed by South-East Asia -7%- and Eastern Mediterranean Region. Almost half of the world population remains at risk of malaria in 2016. Of the 91 countries reporting indigenous malaria cases, 15 countries carried 80% of the global malaria burden. In 2016, 445 000 malaria deaths were estimated worldwide, and 91% were in Africa. Almost 66% of these deaths involved children under five year-old, a population that is particularly vulnerable to this disease. Despite significant funding for malaria control in 2015, the number of indigenous malaria cases has progressively increased since 2013 after a significant decrease between 2000 and 2013 and the number of malaria-related deaths has stagnated since 2015. Emergence of resistance to most antimalarial drugs used in prevention or treatment has been observed. Malaria control and elimination require sustained long-term efforts.
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