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Updated: Jan 26, 2026

Prehospital Thrombolysis: A Manual from Berlin
Published on: November 26, 2013
Lifting the fog in intermediate-risk (submassive) PE: full dose, low dose, or no thrombolysis?
Amyn Bhamani1, Joanna Pepke-Zaba2, Karen Sheares2,3
1Department of Respiratory Medicine, Basildon and Thurrock University Hospital, Basildon, Essex, SS16 5NL.
Abstract:
Acute pulmonary embolism (PE) is a disease frequently encountered in clinical practice. While the management of haemodynamically stable, low risk patients with acute PE is well established, managing intermediate disease often presents a therapeutic dilemma. In this review, we discuss the various therapeutic options available in this patient group. This includes thrombolysis, surgical embolectomy and catheter directed techniques. We have also explored the role of specialist PE response teams in the management of such patients. .
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