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Green tea extract for treatment of cancers: A systematic review protocol

Kai Cheng1, Nan-Nan Chi1, Jun-Dong Liu2

  • 1Second Ward of Gastroenterology Department.

Medicine
|April 16, 2019
PubMed
Abstract

Insights

This systematic review evaluates the efficacy and safety of green tea extract (GTE) for cancer patients. The findings will clarify GTE

Area of Science:

  • Oncology
  • Pharmacology
  • Evidence-based Medicine

Background:

  • Previous studies suggest green tea extract (GTE) may benefit cancer patients.
  • The clinical efficacy and safety of GTE for various cancers remain inconclusive.

Purpose of the Study:

  • To systematically review and synthesize data from clinical studies on the efficacy and safety of GTE in cancer treatment.
  • To provide a comprehensive overview of current evidence to guide future research and clinical practice.

Main Methods:

  • Systematic review and meta-analysis of randomized controlled trials and case-control studies.
  • Comprehensive literature search across multiple databases (CENTRAL, EMBASE, MEDLINE, CINAHL, AMED, CBM) up to February 1, 2019.
  • Data extraction and risk of bias assessment using standardized forms and the Cochrane risk of bias tool.

Main Results:

  • The primary outcome measure is the overall response rate.
  • Secondary outcomes include overall survival, progression-free survival, disease control rate, and adverse events.

Conclusions:

  • This systematic review will elucidate the efficacy and safety profile of GTE in cancer patients.
  • Results are expected to inform future research directions and potential clinical applications of GTE in oncology.

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