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Forward Genetic Approaches in Chlamydia trachomatis
Published on: October 23, 2013
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ChlamBase: a curated model organism database for the Chlamydia research community
Tim Putman1, Kevin Hybiske2, Derek Jow3
1Center for Genome Research and Biocomputing, Oregon State University, Corvallis, OR, USA.
Database : the Journal of Biological Databases and Curation
|April 16, 2019
Summary
Researchers developed ChlamBase, a new bioinformatics database for Chlamydia genomics and proteomics. This model organism database integrates diverse data and allows community contributions for advancing Chlamydia research.
Area of Science:
- Microbiology
- Bioinformatics
- Genomics
Background:
- Chlamydia species present unique biological characteristics and rapidly expanding genomic/proteomic data.
- Major public databases lack specialized bioinformatic tools for Chlamydia research needs.
Purpose of the Study:
- To develop a dedicated model organism database for the Chlamydia research community.
- To provide a centralized platform for accessing and integrating Chlamydia genomic and proteomic information.
- To facilitate user contributions for ongoing data enrichment.
Main Methods:
- ChlamBase was built using the WikiGenomes application framework and Wikidata.
- Integrated data from multiple external databases.
- Extracted and structured data from scientific literature not available elsewhere.
Main Results:
- ChlamBase offers a central access point for Chlamydia genomic and proteomic data.
- The database integrates diverse data sources, including literature-derived information.
- ChlamBase enables community-driven annotation and data submission.
Conclusions:
- ChlamBase addresses the need for specialized bioinformatics resources for Chlamydia research.
- The platform enhances data accessibility and integration for the research community.
- Community involvement in ChlamBase will foster continued discovery in Chlamydia biology.
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