Analysis of Selected Endocrine Disrupters Fraction Including Bisphenols Extracted from Daily Products, Food Packaging...

Area of Science:

• Environmental Chemistry
• Analytical Chemistry
• Toxicology

Background:

• Endocrine-disrupting chemicals (EDCs), particularly bisphenols, are prevalent micropollutants in food and environmental samples.
• Their presence in surface water, wastewater, and plastic products poses risks to ecosystems and human health.
• Advanced analytical techniques for EDC detection are often time-consuming and complex.

Purpose of the Study:

• To develop and demonstrate a rapid, preliminary screening method for EDCs, focusing on bisphenols.
• To establish an analytical protocol for the selective isolation and analysis of low-molecular mass micropollutants.
• To enable fast classification of complex samples for potential EDC contamination.

Main Methods:

• Optimized solid-phase extraction (SPE) for selective isolation, purification, and pre-concentration of target EDC fractions.
• Selective temperature-dependent inclusion chromatography coupled with HPLC-UV-Vis-DAD for sample analysis.
• Utilized internal standard quantification and integrated chromatographic profile areas for sample classification.

Main Results:

• The developed protocol effectively estimates EDC fractions in diverse samples, including food products, daily use items, and environmental matrices.
• Chromatographic experiments showed strong interactions between bisphenols and cyclodextrin derivatives.
• The method demonstrated the emission of detectable low-molecular mass compounds from various daily use products.

Conclusions:

• The proposed analytical protocol provides a fast and efficient means for preliminary screening and classification of samples for EDC presence.
• This method can aid in prioritizing samples for more advanced, targeted analyses.
• Addressing micropollutants, especially microplastic-based EDCs, in wastewater and ecosystems is crucial.